ArticleHealth science reports2026
The Landscape of Radiofrequency Technology for Skin Rejuvenation.
Article in Health science reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Innovative Facial Contouring Using a Monopolar Radiofrequency Device with Continuous Water Cooling: An Integrated Clinical and Preclinical Study.International journal of molecular sciences · 2026Trial
- Objective and subjective retrospective evaluation of XERF, a novel single-shot dual-frequency non-invasive monopolar radiofrequency.Lasers in medical science · 2026Article
- Comparative study of histological differences according to monopolar radiofrequency tip width.Lasers in medical science · 2026Article
- The Landscape of Radiofrequency Technology for Skin Rejuvenation.Health science reports · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and Aims: Aging skin is characterized by reduced tissue volume, weakened fibrous support, and increased laxity, leading to wrinkles and sagging. While surgical methods are effective, noninvasive techniques like radiofrequency (RF) have gained popularity due to their safety, minimal recovery time, and natural-looking results. This review aims to elucidate the mechanisms, classifications, and clinical efficacy of monopolar, bipolar, and multipolar RF systems in skin rejuvenation. Methods: A systematic review was conducted in electronic databases, including PubMed and Web of Science, to comprehensively analyze the literature on radiofrequency for skin rejuvenation. The methodologies, outcomes, and conclusions of the identified studies were summarized and compared. Results: RF technology delivers targeted thermal energy to the dermal layer, inducing collagen contraction and stimulating neocollagenesis, thus improving skin texture and elasticity. Monopolar RF achieves deep tissue penetration (up to 20 mm) but requires precise energy modulation to minimize discomfort. Bipolar RF offers localized treatment with reduced penetration depth (1-4 mm), enabling safer home-use applications. Multipolar RF, particularly microneedle-based systems, combines mechanical injury with thermal remodeling to enhance collagen production while sparing epidermal integrity. Despite the high safety profile, potential risks and complications exist, emphasizing the need for individualized treatment and experienced practitioners. Conclusion: Radiofrequency technology is an integral component of skin rejuvenation, whose efficacy depends critically on the customization of treatment parameters and the expertise of the practitioner. Future research should focus on optimizing parameters, elucidating underlying mechanisms, and exploring combination therapies to further enhance clinical efficacy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.