Evidence map›Paper›PMID 41467184›Full record

ArticleiScience2025

A higher serum lipase cut-off improves the diagnosis of acute pancreatitis in patients with non-epigastric abdominal pain.

Sarah Jahangir, Arti Anand, Mohamed Elmallahy, Hally Chaffin, Prasad Rajalingamgari, Mahmoud Morsy, Megan Summers, Shubham Trivedi, Yu-Hui Chang, Christine Snozek and 1 more

Abstract read
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In one paragraph

Article in iScience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Sarah JahangirDepartment of Medicine, Mayo Clinic, Scottsdale, AZ, USA.
Arti AnandDepartment of Medicine, Mayo Clinic, Scottsdale, AZ, USA.
Mohamed ElmallahyDepartment of Medicine, Mayo Clinic, Scottsdale, AZ, USA.
Hally ChaffinDepartment of Medicine, Mayo Clinic, Scottsdale, AZ, USA.
Prasad RajalingamgariDepartment of Medicine, Mayo Clinic, Scottsdale, AZ, USA.
Mahmoud MorsyDepartment of Medicine, Mayo Clinic, Scottsdale, AZ, USA.
Megan SummersDepartment of Medicine, Mayo Clinic, Scottsdale, AZ, USA.
Shubham TrivediDepartment of Medicine, Mayo Clinic, Scottsdale, AZ, USA.
Yu-Hui ChangDepartment of Clinical Trials and Biostatistics, Mayo Clinic, Scottsdale, AZ, USA.
Christine SnozekDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Scottsdale, AZ, USA.
Vijay P SinghDepartment of Medicine, Mayo Clinic, Scottsdale, AZ, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute pancreatitis (AP) may present with non-epigastric, i.e., atypical pain. Current guidelines recommend the same diagnostic lipase cut-off irrespective of pain location, which increases cross-sectional imaging requirements. 863 emergency department patients with serum lipases >3-times upper-limit of normal (ULN) were accrued over 6 years. Alternate lipase cut-offs for atypical pain were studied in training (

Indexed as

EndocrinologyPublic health

Identifiers

PMID41467184
PMCPMC12744255

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.