Evidence map›Paper›PMID 41467177›Full record

ArticleiScience2025

SIRPB1 is transcriptionally regulated by USF2 and promotes cutaneous malignant melanoma tumorigenicity through SOCS1/STAT3 signaling.

Danmei Ning, Dong Xie, Shuqi Huang, Pingxiu He, Xiaoxiao Chen, Nanfei Feng, Chuan Wan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Danmei NingDepartment of Dermatology, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi Province 330006, P.R. China.
Dong XieDepartment of Plastic Surgery, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi Province 330006, P.R. China.
Shuqi HuangDepartment of Dermatology, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi Province 330006, P.R. China.
Pingxiu HeDepartment of Pathology, Dermatology Hospital of Jiangxi Province, Nanchang, Jiangxi Province 330001, P.R. China.
Xiaoxiao ChenDepartment of Dermatology, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi Province 330006, P.R. China.
Nanfei FengDepartment of Dermatology, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi Province 330006, P.R. China.
Chuan WanDepartment of Dermatology, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi Province 330006, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Melanocyte-derived cutaneous malignant melanoma (MM) is the most common malignancy of the skin and the leading cause of skin cancer-related deaths worldwide. Although SIRPB1 is involved in tumorigenesis and development in various cancers, its role in cutaneous MM is still not elucidated. Our work investigates the role of SIRPB1 in the pathogenesis of cutaneous MM and explores its specific function mechanism. SIRPB1 downregulation inhibited the proliferation, migration, and invasion of melanoma cells, both

Indexed as

Biological sciencesCancer

Identifiers

PMID41467177
PMCPMC12744269

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.