Biofabrication of zinc-reinforced PLA scaffolds by FDM for bone tissue engineering.

Sahar Halevi, Noam Ribak, Avia Lavon, Sivan Hazan, Galit Katarivas Levy

Abstract read

In one paragraph

Article in Regenerative biomaterials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sahar HaleviDepartment of Biomedical Engineering, Ben-Gurion University of the Negev, Beer-Sheva 8499000, Israel.

Noam RibakDepartment of Biomedical Engineering, Ben-Gurion University of the Negev, Beer-Sheva 8499000, Israel.

Avia LavonDepartment of Biomedical Engineering, Ben-Gurion University of the Negev, Beer-Sheva 8499000, Israel.

Sivan HazanDepartment of Biomedical Engineering, Ben-Gurion University of the Negev, Beer-Sheva 8499000, Israel.

Galit Katarivas LevyDepartment of Biomedical Engineering, Ben-Gurion University of the Negev, Beer-Sheva 8499000, Israel.ORCID https://orcid.org/0000-0003-4711-7348

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The development of biodegradable scaffolds with improved mechanical and biological performance is a pressing challenge in bone tissue engineering. Poly(lactic acid) (PLA), widely used in fused deposition modelling (FDM) due to its processability and biocompatibility, lacks sufficient bioactivity and strength for demanding applications. In this study, we fabricated and evaluated zinc-reinforced PLA composite filaments (5-30 wt% Zn) via melt extrusion and FDM to define a practical printability window and establish process-structure-function relationships aimed at enhancing osteointegration and stability. Microstructure, density, and crystallinity were characterized by optical microscopy/scanning electron microscope, Archimedes' principle, X-ray diffraction, and differential scanning calorimetry. Mechanical performance was quantified by tensile testing of standardized samples and compression of gyroid lattices.

Indexed as

biodegradable scaffoldsbone tissue engineeringfused deposition modellingpoly(lactic acid)zinc-reinforced composites

Identifiers

PMID41467041

DOI10.1093/rb/rbaf123

PMCPMC12744395

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.