ReviewFundamental research2025
Heating up the immune battle: Magnetic hyperthermia against cancer.
Review in Fundamental research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed.
- Nanoparticle Engineering in Modern Vaccinology: From Delivery Platforms to Immune-Programming Architectures.Molecules (Basel, Switzerland) · 2026Review
- Engineering the tumor immune landscape: Translating non-invasive physical stimulation into tumor-associated macrophage-targeted cancer immunotherapy.Bioengineering & translational medicine · 2026Review
- Magnetic Fields in Cancer Therapy: Mechanistic Insights, Signaling Pathways, and Evidence from Clinical and In Vitro Studies.Pharmaceutics · 2026Review
- Nanomedicine Meets Immunotherapy: Advancing Adoptive Cell Therapy with Nanoparticles in the Treatment of Cancer with Sustainability Perspectives.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Theranostics in the management of colorectal cancer.Discover nano · 2025Review
- Nanoparticle-mediated magnetic hyperthermia in the treatment of neurological disorders.Nanomedicine (London, England) · 2025Review
- Physical biomedical science.Fundamental research · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Magnetic hyperthermia (MH) utilizes magnetic iron oxide nanomaterials (MIONs) to generate nano-scale heat and boost reactive oxygen species production within cells exposed to an external alternating magnetic field. Unlike conventional thermal ablation therapies that produce heat on a macro-scale, MIONs act as point source of heat inside cells, which enables MIONs-mediated MH to modulate cellular functions and fate with precision in real-time. With key benefits such as deep tissue penetration and the ability to regulate processes in a temporal-spatial and quantifiable manner, MH is now emerging as a new cancer therapy. Most intriguing is the apparent ability for MH to alter specific biological pathways associated with an anti-tumor immune response. Research efforts are now accelerating to render MH applicable to the clinical setting, with the objective of supporting the treatment of common cancers such as hepatocellular carcinoma (HCC). In this perspective paper, we highlight the recent progress made in MH, with a particular focus on its ability to manipulate anti-tumor immune mechanisms and the therapeutic advantages demonstrated thus far for HCC. We explore the current challenges in this field, and provide our perspective on the outlook for MH and its role in cancer treatment.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.