Evidence map›Paper›PMID 41466933›Full record

ArticleCureus2025

Purpura Fulminans Due to Escherichia coli Septicemia in Relapsed Acute Myeloid Leukemia: An Unusual Case of Protein C Deficiency and Disseminated Intravascular Coagulation.

Tarek Zieneldien, Sophia Ma, Karanbir Singh, Adeshpal Singh, Janice Kim, Ana Velez, John Greene

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Carrageenan-induced immunothrombotic models in rodents (Review).Experimental and therapeutic medicine · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Tarek ZieneldienSchool of Medicine, Johns Hopkins University, Baltimore, USA.
Sophia MaSchool of Medicine, Johns Hopkins University, Baltimore, USA.
Karanbir SinghInternal Medicine, Government Medical College, Amritsar, IND.
Adeshpal SinghInternal Medicine, Government Medical College, Amritsar, IND.
Janice KimCollege of Osteopathic Medicine, Michigan State University, East Lansing, USA.
Ana VelezInfectious Disease, Moffitt Cancer Center, Tampa, USA.
John GreeneInternal Medicine, Moffitt Cancer Center, Tampa, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpura fulminans (PF) is a rare and life-threatening condition characterized by rapid development of cutaneous microvascular thrombosis and skin necrosis, typically associated with disseminated intravascular coagulation (DIC). Here, we present a case of PF in an adult patient with relapsed acute myeloid leukemia (AML) who developed

Indexed as

acute myeloid leukemiacritical care dermatologydisseminated intravascular coagulationescherichia coliimmunocompromised hostprotein c deficiencypurpura fulminanssepsis

Identifiers

PMID41466933
PMCPMC12744358

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.