Evidence map›Paper›PMID 41466916›Full record

ArticleCureus2025

Complete Remission After Palliative Radiation and Chemotherapy in Stage IV BRCA1-Positive Pancreatic Cancer: A Case of a Patient Who Was Cured 11 Years After Treatment.

Simranjit Kaur, Chrystal Huynh, Victoria Pan, Khalid Hirmiz

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Simranjit KaurOncology, Windsor Regional Hospital, Windsor, CAN.
Chrystal HuynhOncology, Windsor Regional Hospital, Windsor, CAN.
Victoria PanOncology, Windsor Regional Hospital, Windsor, CAN.
Khalid HirmizOncology, Windsor Regional Hospital, Windsor, CAN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pancreatic cancer is associated with high mortality rates due to its markedly aggressive nature and typically late diagnosis. This is especially true for stage IV, in which the prognosis averages only a few months of median survival. We report a case that highlights the benefits of offering palliative treatment for terminal-stage pancreatic cancer to achieve unexpectedly prolonged survival and potential cure. A complete response was observed following low-dose palliative radiation and chemotherapy in a 54-year-old female patient who was BRCA1-positive and presented with stage IV pancreatic adenocarcinoma. There was no residual cancer or further metastasis seen on follow-up computed tomography (CT) imaging. The patient remained cancer-free and asymptomatic 11 years after the initial diagnosis.

Indexed as

brca genechemotherapycomplete remissionpalliative radiationpancreatic cancerprognosis

Identifiers

PMID41466916
PMCPMC12744686

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.