ArticleBioinformation2025
Informed consent: Navigating the bioethical complexities of clinical research.
Article in Bioinformation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Informed consent (IC) has traditionally been regarded as the fundamental principle of ethical clinical research involving human subjects. This article explores the limitations of the IC, assesses the need for a comprehensive ethical framework and proposes a roadmap for developing a framework that holistically safeguards participants' rights, safety and well-being. The evolving nature of medical technology and complex decision-making situations necessitate a more comprehensive approach to research ethics. This review emphasizes the need for a procedural plan to structure moral deliberations and address potential conflicts between ethical values. By integrating ethical values and benchmarks, a systematic and consistent approach is required to uphold ethical integrity in clinical research beyond the limitations of informed consent.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.