Evidence map›Paper›PMID 41466701›Full record

ArticleBioinformation2025

Retrospective cohort study on long-term anticoagulation therapy for bleeding complications among atrial fibrillation patients.

Megha Joy, Bethamcherla Bala Chandrudu, Mohamed Thoufeek Hussain Amjat Ibrahim, Richard Fleming, Harish Sidharth Veerachamy

Abstract read
In one paragraph

Article in Bioinformation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Megha JoyDepartment of Internal Medicine, Queen Elizabeth Queen Mother Hospital, Margate, United Kingdom.
Bethamcherla Bala ChandruduDepartment of Medical Physiology, Visvabharathi Medical College and General Hospital, Penchikalapadu, Andhra Pradesh, India.
Mohamed Thoufeek Hussain Amjat IbrahimDepartment of Vascular Surgery, Apollo main hospital, Karpaga Vinayaga Institute of medical science and research center, Tamil Nadu, India.
Richard FlemingDepartment of General Medicine, Snehadaan Hospital, Bengaluru, Karnataka.
Harish Sidharth VeerachamyDepartment of General Medicine, Tirunelveli Medical College, Tamil Nadu, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The frequencies and contributing factors to bleeding complications among atrial fibrillation patients on a regimen of long-term oral anticoagulants is of interest. The medical records for 142 patients treated with either warfarin or direct oral anticoagulants (DOACs) were assessed over a period of three years. Major and minor bleeding episodes were associated with instability of the international normalized ratio (INR), the type of anticoagulant medication, and individual patient characteristics. The bleeding complications were observed to occur more frequently with patients presenting with unstable INR values and those treated with warfarin in contrast to DOACs patients. Thus, the importance of a tailored anticoagulation regimen to address bleeding complications in atrial fibrillation is shown.

Indexed as

anticoagulationatrial fibrillationbleeding riskDOACsINR fluctuationlong-term treatmentWarfarin

Identifiers

PMID41466701
PMCPMC12744413

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.