ArticleBioinformation2025
Urinary nephrin - An emerging novel biomarker in early detection of diabetic nephropathy: A review.
Article in Bioinformation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Combined Mesenchymal Stem Cells and Low-Energy Shock Wave Therapy Significantly Reduced Inflammation, Oxidative Stress and Preserved Podocytes in Diabetic Nephropathy.Life (Basel, Switzerland) · 2026Article
- Biomarkers in Diabetic Kidney Disease: Early Detection, Prognostic Assessment, and Integration with Multi-Omics Signatures.Life (Basel, Switzerland) · 2026Review
- Urinary nephrin as an early biomarker of podocyte dysfunction in essential hypertension: a stage-stratified study from Bukhara, Uzbekistan.Frontiers in cardiovascular medicine · 2026Article
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Authors and funding
2 authors.
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Abstract
Diabetic nephropathy is a microvascular complication of uncontrolled diabetes mellitus. Diabetic nephropathy is characterized by persistent albuminuria, hypertension and a progressive decline in the glomerular filtration rate. Early detection of diabetic nephropathy is crucial for the management of complications. Urinary Nephrin is an emerging biomarker that has been implicated in early detection of diabetic nephropathy. Nephrin is a podocyte-specific protein that maintains glomerular filtration barrier integrity. Alterations in Nephrin expression and urinary excretion are signs of renal impairment in diabetic nephropathy. Therefore, it is of interest to establish a biological reference interval and standardize the assay method. Hence, an update on this emerging biomarker is relevant.
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