Evidence map›Paper›PMID 41466697›Full record

ArticleBioinformation2025

Serum Nogo - A as a predictor of neurological recovery in spinal cord injury.

Shah Waliullah, Akash Singh, Devarshi Rastogi, Deepak Kumar, Ashish Kumar, Amar Chandra Sharma, Zeenat Ara, Uday Raj

Abstract read
In one paragraph

Article in Bioinformation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Shah WaliullahDepartment of Orthopaedic Surgery, King George's Medical University, Lucknow, Uttar Pradesh-226003, India.
Akash SinghDepartment of Orthopaedic Surgery, King George's Medical University, Lucknow, Uttar Pradesh-226003, India.
Devarshi RastogiDepartment of Orthopaedic Surgery, King George's Medical University, Lucknow, Uttar Pradesh-226003, India.
Deepak KumarDepartment of Orthopaedic Surgery, King George's Medical University, Lucknow, Uttar Pradesh-226003, India.
Ashish KumarDepartment of Orthopaedic Surgery, King George's Medical University, Lucknow, Uttar Pradesh-226003, India.
Amar Chandra SharmaDepartment of Trauma Surgery, King George's Medical University, Lucknow, Uttar Pradesh-226003, India.
Zeenat AraDepartment of Orthopaedic Surgery, King George's Medical University, Lucknow, Uttar Pradesh-226003, India.
Uday RajDepartment of Orthopaedic Surgery, King George's Medical University, Lucknow, Uttar Pradesh-226003, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spinal Cord Injury (SCI) leads to severe neurological impairment due to irreversible damage to spinal axons and limited Spinal Cord Injury (SCI) causes severe neurological impairment due to irreversible axonal damage and limited regenerative capacity. Current treatments, including surgical decompression and neuroprotective agents, have limited effectiveness, with no consensus on the optimal therapeutic combination. Anti-Nogo-A therapies show promise in preclinical studies, but their clinical efficacy remains uncertain. Emerging evidence suggests that serum Nogo-A levels may serve as prognostic biomarkers for neurological recovery in SCI patients. This study explores the potential of targeting the Nogo A/Nogo receptor pathway to enhance axonal regeneration and support the development of personalized treatment strategies.

Indexed as

neurological recoveryprognostic biomarker and therapeutic targetreceptor antagonists and gene therapyserum nogo-aSpinal cord injury

Identifiers

PMID41466697
PMCPMC12744469

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.