ArticleBioinformation2025
Study of antibiotic consumption using a novel unit among indoor pediatric patients in India.
Article in Bioinformation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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4 authors.
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Abstract
Unlike adult population, the Defined Daily Dose/100 Patient Days (DDD/100 PD) cannot be used as a standard unit in pediatric studies. In this study, we measured antibiotic consumption using standard unit's used- DDD/100 PD and DDD per 1000 Kilogram-Days (DDD/1000 Kg-D) and a novel unit- DDD/100 PD/ Mean Body Weight (DDD/100 PD/MBW). The study cohort was sub-divided into four sub-cohorts (n1=100, n2=100, n3=100, n4=92) with increasing mean body weight (in Kgs) of 6.21±1.46, 9.56±1.00, 13.84±1.59 and 22.94±5.18, respectively. The weight based sub-cohorts sought to explore the most suitable unit for the paediatric population. The Pearson correlation coefficient between DOT and DDD/100 PD, DDD/1000 Kg-D and DDD/100 PD/MBW, were -0.859, 0.981 and 0.975, respectively. Thus, DDD/100 PD/MBW is a novel unit in paediatric drug quantification independent of body weight and age.
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