ArticleBMC psychology2025
The effects of posttraumatic stress symptoms on anxiety and depression in patients with breast cancer: mediating role of negative interpretation bias.
Article in BMC psychology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
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6 authors.
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Abstract
backgroundThis study examined the associations between posttraumatic stress symptoms (PTSS), anxiety, depression, and negative interpretation bias in breast cancer patients, with a specific focus on the potential mediating role of negative interpretation bias.
methodsEighty breast cancer patients completed a cross-sectional assessment including the Impact of Event Scale (IES), the Hospital Anxiety and Depression Scale (HADS), and an ambiguous emotional face recognition task. Participants were categorized into PTSS and non-PTSS groups based on IES scores. Data were analyzed using descriptive statistics, independent-samples t-tests, ANOVA, and mediation analyses (PROCESS Model 4, 5,000 bootstraps, 95% CI).
resultsPatients with PTSS reported significantly higher levels of anxiety and depression, and demonstrated a stronger tendency to interpret ambiguous emotional expressions in a negative manner. Negative interpretation bias partially mediated the association between PTSS and emotional distress.
conclusionsBreast cancer patients with PTSS tend to experience heightened emotional distress, which may be partly accounted for by negative interpretation bias. Additional psychological and physiological mechanisms may also contribute.
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