Evidence map›Paper›PMID 41466349›Full record

ArticleMalaria journal2025

Durability and effectiveness of insecticide-treated nets in Mali: a longitudinal gSG6-P1 biomarker-based assessment of children's exposure to Anopheles bites.

Ibrahim Traore, Moussa B M Cisse, Dipomin François Traoré, Yacouba Dansoko, Tidiani Sinayoko, Amadou Diakité, Lazeni Konaté, Alou Yacouba Sangaré, Jean-Marie Sanou, Alice Dembelé and 6 more

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In one paragraph

Article in Malaria journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Ibrahim TraoreLaboratoire de Biologie Moléculaire Appliquée, Université des Sciences, des Techniques et des Technologies de Bamako, Bamako, Mali. ibrahim.traore@lbma.edu.ml.
Moussa B M CisseLaboratoire de Biologie Moléculaire Appliquée, Université des Sciences, des Techniques et des Technologies de Bamako, Bamako, Mali.
Dipomin François TraoréLaboratoire Trans-Risk/Institut Pierre Richet, Institut National de Santé Publique, Bouaké, Côte d'Ivoire.
Yacouba DansokoLaboratoire de Biologie Moléculaire Appliquée, Université des Sciences, des Techniques et des Technologies de Bamako, Bamako, Mali.
Tidiani SinayokoLaboratoire de Biologie Moléculaire Appliquée, Université des Sciences, des Techniques et des Technologies de Bamako, Bamako, Mali.
Amadou DiakitéLaboratoire de Biologie Moléculaire Appliquée, Université des Sciences, des Techniques et des Technologies de Bamako, Bamako, Mali.
Lazeni KonatéLaboratoire de Biologie Moléculaire Appliquée, Université des Sciences, des Techniques et des Technologies de Bamako, Bamako, Mali.
Alou Yacouba SangaréLaboratoire de Biologie Moléculaire Appliquée, Université des Sciences, des Techniques et des Technologies de Bamako, Bamako, Mali.
Jean-Marie SanouLaboratoire de Biologie Moléculaire Appliquée, Université des Sciences, des Techniques et des Technologies de Bamako, Bamako, Mali.
Alice DembeléLaboratoire de Biologie Moléculaire Appliquée, Université des Sciences, des Techniques et des Technologies de Bamako, Bamako, Mali.
Mariam S SangaréLaboratoire de Biologie Moléculaire Appliquée, Université des Sciences, des Techniques et des Technologies de Bamako, Bamako, Mali.
Aldiana Kadidia MaigaLaboratoire de Biologie Moléculaire Appliquée, Université des Sciences, des Techniques et des Technologies de Bamako, Bamako, Mali.
Mamadou SowLaboratoire de Biologie Moléculaire Appliquée, Université des Sciences, des Techniques et des Technologies de Bamako, Bamako, Mali.
Mahamadou MagassaProgramme National de Lutte contre le Paludisme, BP E3206, Bamako, Mali.
Franck RemouéUMR MIVEGEC, Université de Montpellier, IRD, CNRS, Montpellier, France.
Ousmane KoitaLaboratoire de Biologie Moléculaire Appliquée, Université des Sciences, des Techniques et des Technologies de Bamako, Bamako, Mali.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInsecticide-treated nets (ITNs) remain a key intervention in malaria prevention. However, their protective effectiveness may decline with physical deterioration, even when usage remains high. This study assessed the impact of ITN physical integrity on children's exposure to Anopheles mosquito bites over a three-year period in Mali, using gSG6-P1 biomarker as an innovative immuno-epidemiological indicator of human exposure.

methodsA three-year prospective cohort study was conducted from 2018, 2019, and 2020 in two rural health districts of Mali: Kéniéba using Yorkool

resultsITN usage remained high (> 75%) across all survey years, but the proportion of serviceable nets declined significantly, particularly for Yorkool

conclusionThis study demonstrates that ITN effectiveness decreases as physical deterioration advances, even when usage is maintained. Monitoring net integrity through the gSG6-P1 biomarker provides an innovative, field-adapted approach to anticipate ITN protection failures and to support evidence-based decision-making in malaria control programmes.

Indexed as

AnophelesInsect Bites and StingsInsecticide-Treated BednetsMalariaMosquito ControlAnimalsBiomarkersChild, PreschoolFemaleHumansInfantInsect ProteinsLongitudinal StudiesMaleMaliProspective StudiesBiomarkersgSG6-P1 peptide, Anopheles gambiaeInsect ProteinsSalivary Proteins and PeptidesAnopheles exposuregSG6-P1Insecticide-treated nets (ITNs)Malaria vector controlNet durability

Identifiers

PMID41466349
PMCPMC12751890

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.