ArticleInternational journal of retina and vitreous2025
Associations between axial length and optical coherence tomography angiography biomarkers.
Article in International journal of retina and vitreous, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- A cross sectional study of optical coherence tomography angiography biomarkers and best corrected visual acuity in epiretinal membrane eyes.International journal of retina and vitreous · 2026Article
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6 authors.
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Abstract
purposeTo determine the associations between axial length (AL) and optical coherence tomography angiography (OCTA)-based eye-related parameters.
methodsA prospective cross-sectional study of the right eye of 6953 individuals between the ages 50 and 97, with a range of AL from 19.1 to 31.7 mm was performed. Central subfield thickness (CST), foveal avascular zone (FAZ) and mean vessel density (mVD) were measured by OCTA. Associations between OCTA-based parameters, eye-related and systemic-related parameters were assessed using one-way ANCOVA, multivariable linear regression analysis and multiple regression analysis.
resultsAL and OCTA-based parameters were negatively correlated with age. Increased AL was associated with increased CST (ß=3.59), decreased FAZ (ß=0.02), and decreased mVD (ß=-0.4) (all p = 0.000). Better best corrected visual acuity (BCVA) was associated with larger FAZ (ß=-0.07) and higher mVD (ß=-3.160) (p = 0.002, p = 0.000). Hypertension and diabetes mellitus correlated with increased mVD (ß=0.5) and decreased mVD (ß=-0.18) respectively (p = 0.000, p = 0.023).
conclusionIncreased AL is associated with lower mVD which may be a potential factor between myopia and poor BCVA.
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