ArticleBMC medical imaging2025
Diagnostic value of shear wave elastography for diabetic peripheral neuropathy: comparison between junior radiologists and senior radiologists.
Article in BMC medical imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- [Value of shear wave elastography in the early diagnosis of DPN in patients with type 2 diabetes mellitus].Zhonghua shao shang yu chuang mian xiu fu za zhi · 2026Article
- Shear Wave Elastography in Musculoskeletal Imaging: A Narrative Review.Journal of clinical medicine · 2026Review
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Authors and funding
7 authors.
Funding
Abstract
backgroundDiabetic peripheral neuropathy (DPN) is a prevalent complication of diabetes mellitus, and is often underdiagnosed because of its variable clinical presentation and operator-dependent diagnostic tools. Shear wave elastography (SWE), which quantitatively evaluates tissue stiffness, has the potential to enhance conventional ultrasound by improving diagnostic accuracy and consistency. Nevertheless, a comprehensive analysis examining the extent to which the integration of SWE with conventional ultrasound can enhance the diagnostic performance of radiologists across varying levels of expertise has yet to be performed.
methodsIn this study, a total of 458 lower extremities from patients with type 2 diabetes were examined via ultrasound and SWE. Four radiologists (two seniors and two juniors) independently assessed the grayscale ultrasound, SWE, and combined images. Diagnostic performance was compared via receiver operating characteristic (ROC) curves and sensitivity and specificity metrics.
resultsSWE measurements revealed significantly greater stiffness of the tibial nerve in the DPN group than in the non-DPN group, with values of 37.30 kPa versus 25.40 kPa (P < 0.001) and corresponding shear wave velocities of 3.54 m/s versus 2.90 m/s (P < 0.001). The combined images improved diagnostic accuracy across all readers. Notably, junior radiologists exhibited a substantial improvement in terms of sensitivity (ΔSensitivity = 25.565, 95% CI: 18.477-32.653, P = 0.004). In contrast, for the senior radiologists, neither the sensitivity nor the specificity significantly increased with increasing integration SWE.
conclusionCombining SWE with conventional ultrasound improves the diagnostic accuracy for DPN and helps reduce performance gaps between junior and senior radiologists. SWE may serve as an effective adjunct to support early detection and consistent evaluation of DPN in clinical practice.
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