Evidence map›Paper›PMID 41466203›Full record

ArticleActa obstetricia et gynecologica Scandinavica2026

The association between different aspects of socioeconomic deprivation and severe maternal morbidity.

Dorothea Geddes-Barton, Rema Ramakrishnan, Raph Goldacre, Marian Knight

Abstract read
In one paragraph

Article in Acta obstetricia et gynecologica Scandinavica, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Dorothea Geddes-BartonNational Perinatal Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.ORCID 0000-0003-0081-7670
Rema RamakrishnanNational Perinatal Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.
Raph GoldacreNuffield Department of Population Health, Oxford University, Oxford, UK.
Marian KnightNational Perinatal Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.

Funding

National Institute for Health and Care Research NIHR303806NIHR Oxford Biomedical Research Centre
6 · The paper itself

Abstract

introductionLiving in a deprived neighborhood is associated with an increased risk of severe maternal morbidity (SMM), but the specific deprivation factors or individual SMM conditions driving this risk remain unclear. This study examined how different domains and subdomains of the Index of Multiple Deprivation (IMD) are associated with SMM, identifying key contributors. MATERIAL AND

methodsWe conducted a nationwide, population-based cohort study using English Hospital Episode Statistics Admitted Patient Care (HES APC) data. The cohort included 4 040 106 women aged 10-55 years who gave birth in NHS facilities in England between January 1, 2013, and March 31, 2023, with pregnancies of ≥20 weeks' gestation. Multilevel multivariable Poisson regression estimated adjusted risk ratios (aRR) and 95% confidence intervals (CI) of composite SMM and key individual SMM conditions for each IMD quintile compared to the least deprived quintile, and aRR (95% CI) of composite SMM in each IMD domain/subdomain quintile compared to the least deprived quintile.

resultsIMD domains showed varying associations with SMM. Income and employment deprivation had the strongest associations, with women living in the most deprived quintile having aRRs of 1.16 (95% CI 1.12-1.20) and 1.15 (95% CI 1.11-1.19) compared to those living in the least deprived quintile, respectively. Contrastingly, high geographical barriers to services were associated with a lower risk of SMM (aRR: 0.92 (95% CI 0.88-0.95)). Sepsis, acute cardiac events, and embolism play a key role in the association between composite deprivation and SMM, with women living in the most deprived areas having risk ratios of 1.43 (95% CI 1.36-1.50), 1.24 (95% CI 1.09-1.41), and 1.97 (95% CI 1.69-2.29), respectively, for each of the conditions, compared to women living in the least deprived areas.

conclusionsThere appears to be a widening gap in the risk of SMM between women living in the least and most deprived areas in England, with sepsis, cardiac events, and embolism having the strongest association with deprivation. Composite measures of area-level deprivation may obscure the diverse impacts of specific deprivation factors, and individual-level socioeconomic measures are needed to clarify pathways contributing to SMM risk.

Indexed as

Pregnancy ComplicationsSocial DeprivationAdolescentAdultChildCohort StudiesEnglandFemaleHumansMiddle AgedPregnancyRisk FactorsSocioeconomic FactorsYoung Adulthealth inequalitiesmaternal healthsevere maternal morbiditysocioeconomic disadvantage

Identifiers

PMID41466203
PMCPMC12856710

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