Trial reportBMC neurology2025
Therapeutic efficacy of 3 dimensions printed orthoses on wrist-hand flexor spasticity in post-stroke hemiplegia: a multi-center stratified clinical study.
Trial report in BMC neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
objectiveThis study mainly aimed to compare the clinical efficacy of 3D-printed orthoses versus low-temperature thermoplastic plate orthoses(LTT)on wrist-hand flexor spasticity post-stroke.
methodsPatients were stratified into three cohorts based on the Modified Ashworth Scale (MAS) grades (1,1+, and 2), with 60 patients per cohort. Patients in each cohort were randomized into treatment and control groups: MAS1 (3D, n = 23; control, n = 24); MAS1+ (3D, n = 24; control, n = 25); MAS2 (3D, n = 25; control, n = 26). Orthoses were worn 4–8 h daily for 6 consecutive weeks, followed by a 6-week post-intervention follow-up. The primary outcome was MAS scores. Visual analogue scale(VAS), passive range of motion(PROM), Fugl-Meyer Assessment(FMA), and swelling scale (SS) scores were secondary outcomes, assessed at baseline, 6 weeks, and after 12 weeks.
resultsAt 6 weeks, significant difference in the MAS scores were observed between groups: effective rates (ERs) were MAS1:71.4% vs. 30.8%, p = 0.006; MAS1+: 63% vs. 37%, p = 0.03. After 12 weeks, significant difference in MAS score changes persisted: ERs were MAS1: 66.7% vs. 33.3%, p = 0.029; MAS1+: 64.7% vs. 35.3%, p = 0.001. Significant difference was observed in the Quebec User Evaluation of Satisfaction with Assistive Technology (QUEST) among the MAS1, MAS1+, and MAS2 cohorts (p < 0.01).
conclusion3D-printed orthoses demonstrated superior efficacy to LTT orthoses in reducing mild-to-moderate (MAS 1, 1+) wrist-hand flexor spasticity post-stroke. For severe spasticity (MAS 2), further optimization of material properties and scanning technology may be necessary.
trial registrationChiCTR-INR-2,300,070,454 (Registered: 4 December 2023).
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.