Evidence map›Paper›PMID 41466156›Full record

ReviewEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2026

Efficacy and safety review of tosufloxacin in the treatment of bacterial infection in children.

Suyun Yong, Mengjie Yang, Mi Zhou

Abstract readReview
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In one paragraph

Review in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Suyun YongDepartment of Pharmacy, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi, China.
Mengjie YangDepartment of Pharmacy, Children's Hospital of Soochow University, Suzhou, China.
Mi ZhouDepartment of Pharmacy, Children's Hospital of Soochow University, Suzhou, China. zhoumi007@126.com.ORCID http://orcid.org/0000-0001-8453-4648

Funding

Shaanxi Pharmaceutical Association Hospital pharmacy high-quality development research project 2023-1-1-3Shaanxi Provincial People's Hospital Science and Technology Development Incubation Funding 2023YJY-64
6 · The paper itself

Abstract

In recent years, the use of antibiotics in pediatric patients has received widespread. Tosufloxacin is a quinolone antimicrobial used to treat pneumonia, otitis media, cholera, and anthrax. Guidelines have recommended that quinolone antimicrobials can be used as alternatives for the treatment of bacterial infections in children. However, due to the potential adverse effects on bones and joints, the clinical application of fluoroquinolones requires further evaluation. This article reviewed the latest clinical evidence on the efficacy and safety of tosufloxacin for treating bacterial infections in children. Pharmacokinetic results suggested that drug clearance and volume of distribution were significantly correlated with body weight in children, and the higher the AUC and C

Indexed as

Anti-Bacterial AgentsBacterial InfectionsFluoroquinolonesNaphthyridinesOxazinesChildChild, PreschoolHumansInfantOtitis MediaTreatment OutcomeAnti-Bacterial AgentsFluoroquinolonesNaphthyridinesOxazinestosufloxacinMacrolide antibioticsMinocyclineMycoplasma pneumoniae pneumoniaOtitis mediaTosufloxacin

Identifiers

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.