Evidence map›Paper›PMID 41466136›Full record

Observational studySurgical endoscopy2026

Through-the-scope twin clip for endoscopic closure of gastrointestinal defects: efficacy, safety, and factors influencing closure speed.

Chenyang Li, Chao Chen, Fuxiu Huang, Ningning Zhang, Tao Wang, Yan Xu, Zhongrui Xu, Hui Zhao, Zhimin Liang, Shuling Li and 1 more

Abstract readObservational Study
In one paragraph

Observational study in Surgical endoscopy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Chenyang LiDepartment of Gastroenterology, The First Medical Center of PLA General Hospital, Beijing, China.
Chao Chen *Department of Gastroenterology, The First Medical Center of PLA General Hospital, Beijing, China. 15900611429@163.com.
Fuxiu Huang *Department of Gastroenterology, The Fourth Medical Center of PLA General Hospital, Beijing, China.
Ningning ZhangDepartment of Gastroenterology, The Fourth Medical Center of PLA General Hospital, Beijing, China.
Tao WangDepartment of Gastroenterology, The First Medical Center of PLA General Hospital, Beijing, China.
Yan XuDepartment of Gastroenterology, The Fourth Medical Center of PLA General Hospital, Beijing, China.
Zhongrui XuDepartment of Gastroenterology, The Fourth Medical Center of PLA General Hospital, Beijing, China.
Hui ZhaoDepartment of Gastroenterology, The Fourth Medical Center of PLA General Hospital, Beijing, China.
Zhimin LiangDepartment of Gastroenterology, The First Medical Center of PLA General Hospital, Beijing, China.
Shuling LiDepartment of Gastroenterology, The First Medical Center of PLA General Hospital, Beijing, China.
Yujie FengDepartment of Gastroenterology, The Fourth Medical Center of PLA General Hospital, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsThis study aimed to evaluate the efficacy, safety, and factors influencing closure speed of the through-the-scope twin clip (TTS-TC) for endoscopic defect closure.

methodsA retrospective observational study was conducted at a single center, involving patients who underwent endoscopic closure using the TTS-TC from December 2022 to December 2024.

resultsTTS-TC was successfully deployed in all 78 patients, yielding a complete closure rate of 98.7% (78/79 defects). The median defect area was 10.5 (6.3-15.8) cm

conclusionsThe TTS-TC emerges as a promising tool for the closure of diverse gastrointestinal defects, offering a new dimension in endoscopic management.

Indexed as

Endoscopy, GastrointestinalSurgical InstrumentsAdultAgedAged, 80 and overEquipment DesignFemaleHumansMaleMiddle AgedOperative TimePostoperative ComplicationsRetrospective StudiesTreatment OutcomeDefect closureEndoscopic closureSuper minimally invasive surgeryThrough-the-scope twin clip

Identifiers

PMID41466136
PMCPMC12881058

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.