Evidence map›Paper›PMID 41466101›Full record

ArticleJournal of the peripheral nervous system : JPNS2026

Patient Outcomes Among Medicare Beneficiaries With Guillain-Barré Syndrome.

Brad Wright, Samantha R Eiffert, Abagail Cirincione, Joshua Nardin, James F Howard, Rebecca E Traub

Abstract read
In one paragraph

Article in Journal of the peripheral nervous system : JPNS, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Patient Outcomes Among Medicare Beneficiaries With Guillain-Barré Syndrome.Journal of the peripheral nervous system : JPNS · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Brad WrightDepartment of Health Services Policy and Management, Arnold School of Public Health, University of South Carolina, Columbia, South Carolina, USA.ORCID https://orcid.org/0000-0002-2674-4951
Samantha R EiffertDivision of Pharmaceutical Outcomes and Policy, University of North Carolina School of Pharmacy, Chapel Hill, North Carolina, USA.ORCID https://orcid.org/0000-0002-8612-3807
Abagail CirincioneDepartment of Health Services Policy and Management, Arnold School of Public Health, University of South Carolina, Columbia, South Carolina, USA.
Joshua NardinDepartment of Neurology, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA.
James F HowardDepartment of Neurology, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA.
Rebecca E TraubDepartment of Neurology, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA.ORCID https://orcid.org/0000-0003-0611-1302

Funding

NINDS NIH HHS 1R21NS119867
6 · The paper itself

Abstract

BACKGROUND AND

aimsUnderstanding of population-level outcomes for patients with Guillain-Barré syndrome (GBS) remains limited. We identified which GBS patients are most likely to experience worse outcomes using the largest and most current GBS cohort in the United States.

methodsThis retrospective cohort study used 2005-2020 fee-for-service Medicare claims to identify individuals newly diagnosed with GBS (N = 16 280). We used three person-level modified Poisson regressions to estimate hospital and intensive care unit (ICU) lengths of stay and GBS episode length as a function of sociodemographic characteristics, comorbid conditions, and year of diagnosis. We also documented hospital-acquired pressure ulcers and deep vein thromboses as quality indicators.

resultsMedian hospital length of stay was 9 days [IQR: 6-18 days] and median GBS episode length was 26 days [IQR: 10-60 days]. Approximately 43% of patients spent time in the ICU, with most of those stays (57%) lasting ≤ 1 week. On average, stays and episodes were significantly longer for men, those with a disability, and those diagnosed with an impulse control disorder, other nervous system diagnoses, or certain cancers, but significantly shorter for Black individuals and those dually eligible for Medicare and Medicaid. Most patients avoided developing pressure ulcers (96%) or deep vein thromboses (91%).

interpretationThe GBS disease course varies significantly among Medicare enrollees. We identified some factors associated with worse GBS outcomes and others suggesting structural barriers to care. Our findings can improve care delivery by helping clinicians identify high-risk patients, facilitate early interventions, and reduce morbidity and mortality.

Indexed as

Guillain-Barre SyndromeLength of StayMedicareAgedAged, 80 and overFemaleHumansIntensive Care UnitsMaleMiddle AgedPressure UlcerRetrospective StudiesUnited StatesVenous Thrombosisfee‐for‐serviceGBSICUlength of staymedicareprognostic factors

Identifiers

PMID41466101
PMCPMC12748927

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.