ArticleMedicine2025
Depression increases the risk of contracting genital herpes and genital wart in U.S. adults: A cross-sectional analysis.
Article in Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Depression is associated with a higher prevalence of self-reported risky sexual behaviors, potentially increasing susceptibility to sexually transmitted infections (STIs). However, epidemiological evidence linking depression to genital herpes or genital warts remains limited. This cross-sectional analysis utilized data from the National Health and Nutrition Examination Survey. Depressive symptoms were assessed using the validated Patient Health Questionnaire-9. STIs were self-reported via audio computer-assisted self-interview in private rooms at the Mobile Examination Center. Multivariable logistic regression models were employed to evaluate associations between depression and genital herpes/warts-related outcomes, supplemented by subgroup analyses to identify vulnerable populations. Adults with depression demonstrated significantly elevated risks of genital herpes (odds ratio = 1.73, 95% confidence interval:1.22-2.45) and genital warts (odds ratio = 1.79, 95% confidence interval:1.36-2.35) compared with nondepressed individuals. Subgroup analyses revealed differential vulnerability across demographic and clinical strata, with females, individuals with postsecondary education, and hypertensive patients exhibiting heightened susceptibility to both infections. Depression was associated with higher odds of genital herpes and genital warts among US adults. These findings underscore the clinical importance of integrating STIs screening into mental health management protocols, particularly among females and individuals with higher educational attainment. Enhanced preventive strategies targeting high-risk sexual behaviors in depressed populations are warranted.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.