Observational studyMedicine2025
Effects of percutaneous large-channel spinal endoscopic decompression on stress response, lumbar stability, and disability index in elderly patients with single-segment degenerative lumbar spinal stenosis.
Observational study in Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study aims to evaluate the effects of percutaneous large-channel spinal endoscopic decompression on stress response, lumbar stability, and disability index in elderly patients with single-segment degenerative lumbar spinal stenosis (LSS). A retrospective analysis was performed on 120 elderly patients with single-segment degenerative LSS treated from January 2020 to January 2024. Fifty-seven underwent percutaneous transforaminal endoscopic discectomy group, and 63 underwent percutaneous large-channel spinal endoscopic decompression (large-channel group). Surgical indicators, complications, stress response, lumbar and leg pain, lumbar function [Japanese Orthopaedic Association (JOA) score, Oswestry Disability Index (ODI) score], and lumbar stability were compared. The large-channel group had shorter operative time and fewer intraoperative fluoroscopy sessions than the percutaneous transforaminal endoscopic discectomy group (P<.05), while intraoperative blood loss and incision length were greater (P<.05). Hospital stay and complication rates showed no difference (P>.05). At 3 days postoperatively, serum NE, DA, and 5-HT levels were elevated in both groups (P<.05) but were lower in the large-channel group (P<.05). Lumbar and leg visual analogue scale scores at 1 week, 3 months, and 6 months were lower than preoperative values in both groups (P<.05), with greater improvement in the large-channel group at 3 and 6 months (P<.05). At 1, 3, and 6 months, JOA scores increased and ODI scores decreased in both groups (P<.05). At 3 and 6 months, JOA scores were higher and ODI scores lower in the large-channel group (P<.05). At 6 months, lumbar curvature, lordosis angle, pelvic tilt, and intervertebral space height improved in both groups (P<.05), with greater gains in the large-channel group (P<.05). Percutaneous large-channel spinal endoscopic decompression for elderly patients with single-segment degenerative LSS can shorten operative time, alleviate stenosis and stress response, improve function, and enhance lumbar stability. Its definite efficacy supports clinical application.
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