Evidence map›Paper›PMID 41465801›Full record

ReviewLife (Basel, Switzerland)2025

Molecular Imaging in Parathyroid Carcinoma Management: A Comprehensive Review.

Petra Petranović Ovčariček, Luca Giovanella, Murat Tuncel, Junko Inoue Inukai, Virginia Liberini, Matija Romić, Désirée Deandreis, Rosaria Maddalena Ruggeri, Flaminia Vocaturo, Alfredo Campennì and 1 more

Abstract readReview
In one paragraph

Review in Life (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Petra Petranović OvčaričekDepartment of Oncology and Nuclear Medicine, University Hospital Center Sestre Milosrdnice, 10000 Zagreb, Croatia.ORCID 0000-0003-1946-2128
Luca GiovanellaDepartment of Nuclear Medicine and Thyroid Center, Gruppo Ospedaliero Moncucco, Via Soldino 5, 6900 Lugano, Switzerland.ORCID 0000-0003-0230-0974
Murat TuncelDepartment of Nuclear Medicine, Hacettepe University, 06230 Ankara, Turkey.ORCID 0000-0003-2352-3587
Junko Inoue InukaiDepartment of Radiology, Kobe University Graduate School of Medicine, 7-5-1, Kusunoki-cho, Chuo-ku, Kobe 650-0017, Hyogo, Japan.
Virginia LiberiniDepartment of Nuclear Medicine, Azienda Ospedaliera S Croce e Carle Cuneo, Via Michele Coppino 26, 12100 Cuneo, Italy.ORCID 0000-0001-9416-6965
Matija RomićDepartment of Oncology and Nuclear Medicine, University Hospital Center Sestre Milosrdnice, 10000 Zagreb, Croatia.ORCID 0009-0007-5221-1634
Désirée DeandreisInstitute Gustave Roussy, 94800 Villejuif, France.
Rosaria Maddalena RuggeriEndocrinology Unit, Department of Human Pathology of Adulthood and Childhood DETEV, University of Messina, Via Consolare Valeria 1, 98125 Messina, Italy.ORCID 0000-0001-8899-684X
Flaminia VocaturoDepartment of Radiological Sciences and Haematology, Section of Nuclear Medicine, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.ORCID 0009-0003-6023-5055
Alfredo CampennìUnit of Nuclear Medicine, Department of Biomedical and Dental Sciences and Morpho-Functional Imaging, University of Messina, 98100 Messina, Italy.ORCID 0000-0002-0177-939X
Martin W HuellnerDepartment of Nuclear Medicine, University Hospital of Zurich, Rämistrasse 100, 8091 Zurich, Switzerland.ORCID 0000-0002-4849-3292

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Parathyroid carcinoma (PC) is an exceedingly rare endocrine malignancy, accounting for less than 1% of all primary hyperparathyroidism (pHPT) cases. It typically presents with pronounced hypercalcemia and markedly elevated parathyroid hormone (PTH) levels. Accurate imaging plays a pivotal role in diagnosis, staging, surgical planning, and long-term surveillance, although differentiating PC from benign disease on imaging remains a significant challenge. A multimodal imaging strategy combining cervical ultrasonography (US) and nuclear medicine techniques provides high sensitivity for lesion detection. Ultrasonography with advanced detective flow imaging allows detailed anatomical assessment and evaluation of vascular patterns of the primary tumor. [

Indexed as

[18F]fluorocholine[99mTc]Tc-MIBIhyperparathyroidismmolecular imagingparathyroid carcinomaPET/CTPET/MRscintigraphytheranosticsultrasonography

Identifiers

PMID41465801
PMCPMC12734229

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.