Evidence map›Paper›PMID 41465643›Full record

ReviewInsects2025

Organic Acid Supplementation in Worker Honeybees (

Gebreamlak Bezabih, Tesfay Atsbha, Solomon Zewdu Altaye, Qingsong Zhou, Jianke Li, Christian W W Pirk, Chaodong Zhu, Yu Fang

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Insects, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Gebreamlak BezabihTigray Agricultural Research Institute, Mekelle P.O. Box 492, Ethiopia.ORCID 0009-0009-0943-858X
Tesfay AtsbhaTigray Agricultural Research Institute, Mekelle P.O. Box 492, Ethiopia.ORCID 0000-0002-1823-0379
Solomon Zewdu AltayeEthiopian Institute of Agricultural Research, Chiro P.O. Box 190, Ethiopia.
Qingsong ZhouKey Laboratory of Zoological Systematics and Evolution, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China.ORCID 0000-0002-7312-1589
Jianke LiState Key Laboratory of Resource Insects, Institute of Apicultural Research, Chinese Academy of Agricultural Sciences, Beijing 100193, China.
Christian W W PirkSocial Insect Research Group (SIRG), Department of Zoology & Entomology, University of Pretoria, Private Bag X20, Hatfield, Pretoria 0028, South Africa.ORCID 0000-0001-6821-7044
Chaodong ZhuKey Laboratory of Zoological Systematics and Evolution, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China.
Yu FangState Key Laboratory of Resource Insects, Institute of Apicultural Research, Chinese Academy of Agricultural Sciences, Beijing 100193, China.ORCID 0000-0002-0018-3279

Funding

the Chinese Academy of Sciences (CAS) for providing financial support through the President's International Followship Initiative, Visiting Scientist program 2024PVB0038
6 · The paper itself

Abstract

Honeybees require diverse nutrients for larval growth, adult development, and colony health. Pollen quality significantly impacts reproduction, productivity, and growth. Bioactive substances from honeybee glands enhance colony health, with recent studies showing that optimal citric acid intake extends lifespan, boosts pollen consumption, accelerates mandibular gland development, and improves royal jelly quality. This review examines organic acid feeding's effects on gland development and overall health, offering insights for beekeeping and supplementary food development to support sustainable apiculture. Research gaps in organic acid supplementation, gland development, and health benefits are identified. The impact of varying organic acid concentrations on 10-HDA biosynthesis in mandibular glands and key regulatory proteins influencing 10-HDA expression is summarized. Findings highlight the benefits of organic acid supplements for worker bee gland development and health, guiding future research and practical applications in beekeeping.

Indexed as

Apis melliferacitric acidcolony resiliencedetoxificationglandular developmentgut microbiotahypopharyngeal glandorganic acidsroyal jellysustainable apiculture

Identifiers

PMID41465643
PMCPMC12734247

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.