Evidence map›Paper›PMID 41465563›Full record

ArticleInternational journal of molecular sciences2025

Adipose-Derived Stem Cell Secretome Attenuates Eosinophilic Inflammation in a Chronic Rhinosinusitis with Nasal Polyps Mouse Model.

Ji-Hwan Park, Hye-Jin Park, Dae Woo Kim, Sung-Dong Kim, Sue Jean Mun, Kyu-Sup Cho

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ji-Hwan ParkDepartment of Otorhinolaryngology and Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Yangsan 50612, Republic of Korea.ORCID 0000-0001-9301-6957
Hye-Jin ParkDepartment of Otorhinolaryngology and Biomedical Research Institute, Pusan National University School of Medicine, Pusan National University Hospital, 179 Gudeok-Ro, Seo-gu, Busan 49241, Republic of Korea.ORCID 0000-0003-4237-6834
Dae Woo KimDepartment of Otorhinolaryngology, Seoul Metropolitan Government Seoul National University Boramae Medical Center, Seoul 07061, Republic of Korea.ORCID 0000-0001-5166-3072
Sung-Dong KimDepartment of Otorhinolaryngology and Biomedical Research Institute, Pusan National University School of Medicine, Pusan National University Hospital, 179 Gudeok-Ro, Seo-gu, Busan 49241, Republic of Korea.ORCID 0000-0002-8436-5722
Sue Jean MunDepartment of Otorhinolaryngology and Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Yangsan 50612, Republic of Korea.ORCID 0000-0003-4486-7178
Kyu-Sup ChoDepartment of Otorhinolaryngology and Biomedical Research Institute, Pusan National University School of Medicine, Pusan National University Hospital, 179 Gudeok-Ro, Seo-gu, Busan 49241, Republic of Korea.

Funding

Pusan National University 202300030001
6 · The paper itself

Abstract

Adipose-derived stem cells (ASCs) and their secretome have been reported to improve allergic airway inflammation. Eosinophilic chronic rhinosinusitis with nasal polyps (ECRSwNP) is characterized by type 2 helper T (Th2)-diven inflammation, which shares similar mechanisms with allergic airway diseases. We assessed the immunomodulatory effects of ASC secretome on an ECRSwNP mouse model. ECRSwNP was induced by ovalbumin (OVA) and

Indexed as

Adipose TissueEosinophiliaEosinophilsNasal PolypsRhinitisSecretomeSinusitisAnimalsChemokine CCL11Chronic DiseaseCytokinesDisease Models, AnimalInflammationMiceMice, Inbred BALB COvalbuminChemokine CCL11CytokinesOvalbuminchemokine CCL11cytokineseosinophilsimmunosuppressionmesenchymal stem cellsmicenasal polypsrhinosinusitissecretome

Identifiers

PMID41465563
PMCPMC12734224

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.