Transcriptional Activity of Genes Related to the Biotransformation Process in the Development of Colorectal Cancer.

Grażyna Janikowska, Tomasz Janikowski, Aleksandra Kuźbińska, Mieszko Opiłka, Urszula Mazurek, Zbigniew Lorenc

Abstract read

In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Grażyna JanikowskaDepartment of Analytical Chemistry, Faculty of Pharmaceutical Sciences in Sosnowiec, Medical University of Silesia, Jagiellońska 4 Street, 41-200 Sosnowiec, Poland.ORCID 0000-0002-2839-174X

Tomasz JanikowskiSilesian College of Medicine in Katowice, Mickiewicza 29 Street, 40-085 Katowice, Poland.

Aleksandra KuźbińskaDepartment of Pathomorphology and Molecular Diagnostics, Faculty of Medical Science in Katowice, Medical University of Silesia, Medyków 18 Street, 40-752 Katowice, Poland.

Mieszko OpiłkaCentrum Medyczne NAVIGARE, Konopnickiej 78 Street, 41-300 Dąbrowa Górnicza, Poland.

Urszula MazurekFaculty of Pharmaceutical Sciences in Sosnowiec, The Karol Godula Upper Silesian Academy of Entrepreneurship in Chorzów, Racławicka 23 Street, 41-506 Chorzów, Poland.

Zbigniew LorencDepartment of General, Colorectal and Polytrauma Surgery, Faculty of Health Sciences in Katowice, Medical University of Silesia, 40-055 Katowice, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colorectal cancer (CRC) remains the third leading cause of mortality among cancer patients in developed countries. Each new study in this field can contribute to better detection, diagnosis, and treatment of this disease. Our study aimed to assess transcriptional activity of genes associated with the biotransformation of xenobiotics and endobiotics in all three phases in the CRC

Indexed as

Colorectal NeoplasmsGene Expression Regulation, NeoplasticAgedBiotransformationFemaleGene Expression ProfilingHumansMaleMiddle AgedReceptors, Aryl HydrocarbonTranscriptomeXenobioticsReceptors, Aryl HydrocarbonXenobioticsadenocarcinomadetoxification phasesgene expressionlarge colon cancer

Identifiers

PMID41465541

DOI10.3390/ijms262412116

PMCPMC12733395

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LicenceCC BY

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.