Evidence map›Paper›PMID 41465534›Full record

ArticleInternational journal of molecular sciences2025

Physicochemical Characterisation of Ceftobiprole and Investigation of the Biological Properties of Its Cyclodextrin-Based Delivery System.

Dariusz Boczar, Wojciech Bocian, Krystian Małek, Małgorzata Milczarek, Agnieszka Ewa Laudy, Katarzyna Michalska

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Dariusz BoczarDepartment of Synthetic Drugs, National Medicines Institute, Chełmska 30/34, 00-725 Warsaw, Poland.ORCID 0000-0002-1881-7356
Wojciech BocianLaboratory for Analysis of Bioactive Compounds, Institute of Organic Chemistry, Polish Academy of Sciences, Kasprzaka 44/52, 01-224 Warsaw, Poland.ORCID 0000-0003-3862-8656
Krystian MałekDepartment of Biomedical Research, National Medicines Institute, Chełmska 30/34, 00-725 Warsaw, Poland.ORCID 0009-0006-2630-7731
Małgorzata MilczarekDepartment of Biomedical Research, National Medicines Institute, Chełmska 30/34, 00-725 Warsaw, Poland.ORCID 0000-0003-1209-9477
Agnieszka Ewa LaudyDepartment of Pharmaceutical Microbiology and Bioanalysis, Medical University of Warsaw, Banacha 1b, 02-097 Warsaw, Poland.ORCID 0000-0002-5989-4462
Katarzyna MichalskaDepartment of Synthetic Drugs, National Medicines Institute, Chełmska 30/34, 00-725 Warsaw, Poland.ORCID 0000-0002-7329-3081

Funding

Ministry of Science and Higher Education 1/2025
6 · The paper itself

Abstract

Ceftobiprole is a novel and promising antibiotic; however, the direct pharmacological use of its native form is limited by its low water solubility. The first part of this study provides a deeper insight into the physicochemical properties of this drug. One- and two-dimensional nuclear magnetic resonance (NMR) spectra in D

Indexed as

Anti-Bacterial AgentsCephalosporinsCyclodextrinsDrug Delivery SystemsHumansHydrogen BondingMagnetic Resonance SpectroscopyMicrobial Sensitivity TestsMolecular Dynamics SimulationAnti-Bacterial AgentsceftobiproleCephalosporinsCyclodextrinsantibacterial activitycapillary electrophoresisceftobiprolecytotoxicitydrug delivery systemmolecular dynamicsNMRSBE-β-CDsolubility

Identifiers

PMID41465534
PMCPMC12733258

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.