Nanomechanical Characterization of E-Cigarette-Induced Lung Endothelial Dysfunction: Roles of Cortactin and Mitochondrial Reactive Oxygen Species.

Mounica Bandela, Xue Geng, Joe G N Garcia, James C Lee, Steven M Dudek

Abstract read

In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mounica BandelaDepartment of Biomedical Engineering, College of Engineering, University of Illinois Chicago, Chicago, IL 60607, USA.ORCID 0000-0002-7839-0948

Xue GengDepartment of Biomedical Engineering, College of Engineering, University of Illinois Chicago, Chicago, IL 60607, USA.ORCID 0000-0003-4924-595X

Joe G N GarciaDepartment of Molecular Medicine, Scripps Research Institute, University of Florida, Jupiter, FL 33458, USA.

James C LeeDepartment of Biomedical Engineering, College of Engineering, University of Illinois Chicago, Chicago, IL 60607, USA.ORCID 0000-0002-7173-4875

Steven M DudekDivision of Pulmonary, Critical Care, Sleep and Allergy, Department of Medicine, University of Illinois Chicago, Chicago, IL 60612, USA.ORCID 0000-0001-5624-0714

Funding

Roles of Tau Oligomers in Alzheimer's VasculopathyR01AG044404 · NIA · UNIVERSITY OF MISSOURI-COLUMBIA · PI LEE, JAMES C · 2014 to 2024

$3.5M

American Heart Association 829814 (M.B.)NIA NIH HHS R01 AG044404NIH P01 HL126609 (J.G.N.G.)NIH R01 HL133059 (S.M.D.)

6 · The paper itself

Abstract

E-cigarettes (E-cigs) are increasing in popularity and are considered a potentially safer alternative to traditional cigarettes. However, prior studies have demonstrated that inhalation of nicotine-containing e-cigs can cause substantial pathophysiologic changes, and "vaping" of some substances has led to severe lung damage. Our group recently described the role of cortactin (

Indexed as

CortactinElectronic Nicotine Delivery SystemsEndothelial CellsLungMitochondriaReactive Oxygen SpeciesHumansCortactinReactive Oxygen Speciesatomic force microscopyelastic propertiesmitochondrial dysfunctionpermeability

Identifiers

PMID41465530

DOI10.3390/ijms262412104

PMCPMC12733622

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.