Evidence map›Paper›PMID 41465529›Full record

ArticleInternational journal of molecular sciences2025

Profound Impact of Local Climatic Conditions on IgE Sensitization Profiles: Evidence from Argentine Cities.

Eszter Sarzsinszky, Paola Smaldini, Marcela Chinigo, María Ardanaz, Pablo Benítez, Ana Ramos, María Eugenia Braviz Lopez, Gonzalo Ramón, Germán Ramón, Thomas Schlederer and 6 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Eszter SarzsinszkyDivision of Immunopathology, Department of Pathophysiology and Allergy Research, Medical University of Vienna, 1090 Vienna, Austria.ORCID 0000-0001-8109-312X
Paola SmaldiniInstituto de Estudios Inmunológicos y Fisiopatológicos-IIFP, Facultad de Ciencias Exactas, Universidad Nacional de La Plata, Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), La Plata 1900, Argentina.ORCID 0000-0002-2734-516X
Marcela ChinigoHospital San Juan de Dios, La Plata 1900, Argentina.ORCID 0009-0005-9990-8602
María ArdanazHospital San Juan de Dios, La Plata 1900, Argentina.
Pablo BenítezHospital San Juan de Dios, La Plata 1900, Argentina.
Ana RamosHospital San Juan de Dios, La Plata 1900, Argentina.
María Eugenia Braviz LopezHospital San Juan de Dios, La Plata 1900, Argentina.
Gonzalo RamónInstituto de Alergia e Inmunología del Sur, Bahía Blanca 8000, Argentina.
Germán RamónInstituto de Alergia e Inmunología del Sur, Bahía Blanca 8000, Argentina.ORCID 0000-0001-9990-8147
Thomas SchledererDivision of Immunopathology, Department of Pathophysiology and Allergy Research, Medical University of Vienna, 1090 Vienna, Austria.
Mikhail TulaevDivision of Immunopathology, Department of Pathophysiology and Allergy Research, Medical University of Vienna, 1090 Vienna, Austria.ORCID 0009-0003-3338-9606
Rudolf ValentaDivision of Immunopathology, Department of Pathophysiology and Allergy Research, Medical University of Vienna, 1090 Vienna, Austria.
Huey-Jy HuangDivision of Immunopathology, Department of Pathophysiology and Allergy Research, Medical University of Vienna, 1090 Vienna, Austria.
Susanne VrtalaDivision of Immunopathology, Department of Pathophysiology and Allergy Research, Medical University of Vienna, 1090 Vienna, Austria.ORCID 0000-0003-4250-8243
Guillermo DocenaInstituto de Estudios Inmunológicos y Fisiopatológicos-IIFP, Facultad de Ciencias Exactas, Universidad Nacional de La Plata, Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), La Plata 1900, Argentina.ORCID 0000-0002-0092-3169
The Allergochip Working Group

Funding

Danube Allergy Research Cluster of the country of Lower Austria 23-75-30016European Regional Development Fund (ERDF) and the Romanian national budget P_37_747INSPIRED (Inovative Strategies for Prevention, diagnosis and therapy of ragweed pollen Induced REspiratoryDiseases COP 2014-2020 92/09.09.2016
6 · The paper itself

Abstract

Allergen sensitization profiles are increasingly affected by environmental and climate changes. This study exemplifies fundamental differences in molecular IgE sensitization profiles in two nearby regions in Argentina with different climatic conditions (La Plata and Bahía Blanca). A cross-sectional study was conducted involving 155 patients with allergic symptoms from La Plata and Bahía Blanca (34.0 ± 11.2 years, female/male: 83/72). Serum samples were analyzed for IgE reactivity using a chip containing 101 micro-arrayed allergen molecules. Statistical analyses were performed to compare allergen-specific IgE levels, sensitization prevalences and reported symptoms. Patients from La Plata-with subtropical weather-showed a higher prevalence of IgE reactivity to house dust mite (HDM) allergens (Der p 23: 74%; Der p 1: 53% and Der p 2: 56%) and more frequently reported asthma (AS) symptoms (40% vs. 24%) than patients from Bahía Blanca. In contrast, patients from Bahía Blanca, with dry and windy weather, exhibited higher sensitization rates to pollen allergens, particularly Phl p 1 (49%) and Ole e 1 (22%) as well as to

Indexed as

AllergensClimateHypersensitivityImmunoglobulin EAdolescentAdultAnimalsArgentinaAsthmaCitiesCross-Sectional StudiesFemaleHumansMaleMiddle AgedYoung AdultAllergensImmunoglobulin Eallergenallergic diseasesallergyArgentinaclimatehouse dust miteIgEmicroarraymolecular allergy diagnosispollensensitization

Identifiers

PMID41465529
PMCPMC12733070

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.