Evidence map›Paper›PMID 41465421›Full record

ArticleInternational journal of molecular sciences2025

The Disruption of

Roberto Martínez-Beamonte, Natalia Guillén, Javier Sánchez-Marco, Luis V Herrera-Marcos, Joaquín C Surra, María A Navarro, Cristina Barranquero, Carmen Arnal, Juan J Puente, Ma Jesús Rodríguez-Yoldi and 6 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Roberto Martínez-BeamonteDepartamento de Bioquímica y Biología Molecular y Celular, Facultad de Veterinaria, Instituto de Investigación Sanitaria de Aragón, Universidad de Zaragoza, E-50013 Zaragoza, Spain.ORCID 0000-0002-8100-5596
Natalia GuillénDepartamento de Bioquímica y Biología Molecular y Celular, Facultad de Veterinaria, Instituto de Investigación Sanitaria de Aragón, Universidad de Zaragoza, E-50013 Zaragoza, Spain.
Javier Sánchez-MarcoDepartamento de Bioquímica y Biología Molecular y Celular, Facultad de Veterinaria, Instituto de Investigación Sanitaria de Aragón, Universidad de Zaragoza, E-50013 Zaragoza, Spain.ORCID 0000-0002-9023-741X
Luis V Herrera-MarcosDepartamento de Bioquímica y Biología Molecular y Celular, Facultad de Veterinaria, Instituto de Investigación Sanitaria de Aragón, Universidad de Zaragoza, E-50013 Zaragoza, Spain.ORCID 0000-0002-4665-9674
Joaquín C SurraInstituto Agroalimentario de Aragón, CITA, Universidad de Zaragoza, E-50013 Zaragoza, Spain.ORCID 0000-0002-5841-0462
María A NavarroDepartamento de Bioquímica y Biología Molecular y Celular, Facultad de Veterinaria, Instituto de Investigación Sanitaria de Aragón, Universidad de Zaragoza, E-50013 Zaragoza, Spain.ORCID 0000-0002-0108-1004
Cristina BarranqueroDepartamento de Bioquímica y Biología Molecular y Celular, Facultad de Veterinaria, Instituto de Investigación Sanitaria de Aragón, Universidad de Zaragoza, E-50013 Zaragoza, Spain.ORCID 0000-0002-8442-8041
Carmen ArnalDepartamento de Patología Animal, Facultad de Veterinaria, Universidad de Zaragoza, E-50013 Zaragoza, Spain.
Juan J PuenteServicio de Bioquímica Clínica, Hospital Clínico Universitario Lozano Blesa, E-50009 Zaragoza, Spain.ORCID 0000-0002-7213-7095
Ma Jesús Rodríguez-YoldiInstituto Agroalimentario de Aragón, CITA, Universidad de Zaragoza, E-50013 Zaragoza, Spain.ORCID 0000-0002-3595-7668
Isabel MendiaraInstituto de Investigación en Ingeniería de Aragón (I3A), Universidad de Zaragoza, E-50018 Zaragoza, Spain.ORCID 0000-0001-8830-6554
Celia DomeñoInstituto de Investigación en Ingeniería de Aragón (I3A), Universidad de Zaragoza, E-50018 Zaragoza, Spain.ORCID 0000-0001-8893-0963
Cristina NerínInstituto de Investigación en Ingeniería de Aragón (I3A), Universidad de Zaragoza, E-50018 Zaragoza, Spain.ORCID 0000-0003-2685-5739
Aron M GeurtsHuman Molecular Genetics Center, Medical College of Wisconsin, Milwaukee, WI 53226, USA.ORCID 0000-0002-4347-2505
Jesús OsadaDepartamento de Bioquímica y Biología Molecular y Celular, Facultad de Veterinaria, Instituto de Investigación Sanitaria de Aragón, Universidad de Zaragoza, E-50013 Zaragoza, Spain.ORCID 0000-0002-8251-8457
Martín LaclaustraDepartamento de Medicina, Facultad de Medicina, Instituto de Investigación Sanitaria de Aragón, Universidad de Zaragoza, E-50009 Zaragoza, Spain.

Funding

CIBER Fisiopatología de la Obesidad y Nutrición CB06/03/1012Gobierno de Aragón B16_23R, B45_23R and GUIA group T53_23RSpanish Ministerio de Ciencia e Innovación PID2022-136414OB-I00Spanish Ministry of Science and Innovation with funds from the European Union NextGenera-tionEU, from the Recovery, Transformation and Resilience Plan PRTR-C17.I1
6 · The paper itself

Abstract

Cytochrome P450, family 7, subfamily b, polypeptide 1 (CYP7B1) is a widely expressed enzyme involved in the hydroxylation of sterols. Generated by transposon technology in zygotes, male rats lacking

Indexed as

25-Hydroxyvitamin D3 1-alpha-HydroxylaseCytochrome P450 Family 7HydroxycholesterolsInsulin-Like Growth Factor Binding Protein 2AnimalsHep G2 CellsHumansLiverMaleRatsTriglycerides25-hydroxycholesterol25-Hydroxyvitamin D3 1-alpha-HydroxylaseCytochrome P450 Family 7HydroxycholesterolsInsulin-Like Growth Factor Binding Protein 2Triglycerides25-hydroxycholesterolCYP7B1HDLIGFBP2LDLRrat

Identifiers

PMID41465421
PMCPMC12732954

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.