ArticleInternational journal of molecular sciences2025
Metallomic Profile of Placental Tissue and Its Association with Maternal and Neonatal Parameters: A Cross-Sectional ICP-OES Study in Lower Silesia.
Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
The placenta, a temporary organ that connects mother and child for nutrient and metabolite exchange, becomes medical waste after birth but can provide valuable metabolic insights. Thirty-three placenta samples were analyzed using ICP-OES to determine concentrations of ten elements, including macro-, micro-, trace, and heavy metals. Results were compared with maternal and neonatal data, including Apgar scores, maternal age, and blood parameters. Correlations were found between elements (e.g., Ca-Mg, Fe-Zn, and Mn-Cu) and between mineral levels and maternal or infant parameters (e.g., Ca-RBC, Mn-Hb, Cu-PLT, and Cu-UA Pi). No quantifiable heavy metals were detected, nor associations with smoking, gestational diabetes, preterm birth, birth weight, or Apgar scores. Findings suggest that maintaining proper blood morphology and preventing anemia in pregnancy requires attention not only to iron but also to Ca
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