Gestational and Lactational Exposure to BPS Triggers Microglial Ferroptosis via the SLC7A11/GPX4 Antioxidant Axis and Induces Memory Impairment in Offspring Mice.

Nuo Xu, Xinxin Guo, Yan Su, Mengfen Pan, Kaixing Lin, Zhensong Ma, Haozhe Zhou, Huaicai Zeng

Abstract read

In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Nuo XuGuangxi Key Laboratory of Environmental Exposomics and Entire Lifecycle Health, School of Public Health, Guilin Medical University, Guilin 541199, China.

Xinxin GuoGuangxi Key Laboratory of Environmental Exposomics and Entire Lifecycle Health, School of Public Health, Guilin Medical University, Guilin 541199, China.

Yan SuGuangxi Key Laboratory of Environmental Exposomics and Entire Lifecycle Health, School of Public Health, Guilin Medical University, Guilin 541199, China.

Mengfen PanGuangxi Key Laboratory of Environmental Exposomics and Entire Lifecycle Health, School of Public Health, Guilin Medical University, Guilin 541199, China.

Kaixing LinGuangxi Key Laboratory of Environmental Exposomics and Entire Lifecycle Health, School of Public Health, Guilin Medical University, Guilin 541199, China.

Zhensong MaGuangxi Key Laboratory of Environmental Exposomics and Entire Lifecycle Health, School of Public Health, Guilin Medical University, Guilin 541199, China.

Haozhe ZhouGuangxi Key Laboratory of Environmental Exposomics and Entire Lifecycle Health, School of Public Health, Guilin Medical University, Guilin 541199, China.

Huaicai ZengGuangxi Key Laboratory of Environmental Exposomics and Entire Lifecycle Health, School of Public Health, Guilin Medical University, Guilin 541199, China.

Funding

National Natural Science Foundation of China grants 82160629; 82460653

6 · The paper itself

Abstract

This study aimed to examine the role of maternal BPS gestational and lactational exposure to BPS in neurotoxicity in offspring

Indexed as

Amino Acid Transport System y+FerroptosisMemory DisordersMicrogliaPhospholipid Hydroperoxide Glutathione PeroxidasePrenatal Exposure Delayed EffectsAnimalsAntioxidantsFemaleLactationMaleMiceMice, Inbred C57BLOxidative StressPregnancyAmino Acid Transport System y+Antioxidantsglutathione peroxidase 4, mousePhospholipid Hydroperoxide Glutathione PeroxidaseSlc7a11 protein, mousebisphenol SferroptosismicroglianeurotoxicitySLC7A11/GPX4

Identifiers

PMID41465379

DOI10.3390/ijms262411953

PMCPMC12733156

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.