Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
14 authors.
Deivison Silva ArgoloLaboratory of Neurochemistry and Cellular Biology, Department of Biochemistry and Biophysics, Institute of Health Sciences, Federal University of Bahia, Av. Reitor Miguel Calmon S/N, Salvador 40231-300, BA, Brazil.ORCID 0000-0003-1186-3429
Lucas Matheus Gonçalves OliveiraLaboratory of Neurochemistry and Cellular Biology, Department of Biochemistry and Biophysics, Institute of Health Sciences, Federal University of Bahia, Av. Reitor Miguel Calmon S/N, Salvador 40231-300, BA, Brazil.ORCID 0000-0003-4876-5566
Cleonice Creusa Dos SantosLaboratory of Neurochemistry and Cellular Biology, Department of Biochemistry and Biophysics, Institute of Health Sciences, Federal University of Bahia, Av. Reitor Miguel Calmon S/N, Salvador 40231-300, BA, Brazil.ORCID 0000-0001-6428-4485
Lilian Vanessa da Penha GonçalvesLaboratory of Neurochemistry and Cellular Biology, Department of Biochemistry and Biophysics, Institute of Health Sciences, Federal University of Bahia, Av. Reitor Miguel Calmon S/N, Salvador 40231-300, BA, Brazil.ORCID 0009-0004-4469-3862
Erick Correia LoiolaCenter of Biotechnology and Cell Therapy, São Rafael Hospital, D'Or Institute for Research and Education (IDOR), Av. São Rafael, 2152-São Rafael, Salvador 41253-190, BA, Brazil.ORCID 0000-0002-7926-795X
Bruno Solano de Freitas SouzaCenter of Biotechnology and Cell Therapy, São Rafael Hospital, D'Or Institute for Research and Education (IDOR), Av. São Rafael, 2152-São Rafael, Salvador 41253-190, BA, Brazil.
George E BarretoNeuroendocrine Pharmacology Lab, Department of Biological Sciences, Faculty of Science and Engineering, University of Limerick, V94 T9PX Limerick, Ireland.
Arthur Morgan ButtSchool of Medicine, Pharmacy and Biomedical Sciences, University of Portsmouth, Portsmouth PO1 2UP, UK.ORCID 0000-0001-7579-0746
Jorge Mauricio DavidDepartment of General and Inorganic Chemistry, Institute of Chemistry, University Federal da Bahia, Salvador 40170-110, BA, Brazil.ORCID 0000-0001-6375-9055
Alexsandro BrancoLaboratory of Phytochemistry, Department of Health, State University of Feira de Santana, Av. Transnordestina, s/n, Feira de Santana 44036-900, BA, Brazil.
Isabella Mary Alves ReisLaboratory of Phytochemistry, Department of Health, State University of Feira de Santana, Av. Transnordestina, s/n, Feira de Santana 44036-900, BA, Brazil.ORCID 0000-0002-0256-3347
Annabel Azevedo-SilvaLaboratory of Phytochemistry, Department of Health, State University of Feira de Santana, Av. Transnordestina, s/n, Feira de Santana 44036-900, BA, Brazil.
Silvia Lima CostaLaboratory of Neurochemistry and Cellular Biology, Department of Biochemistry and Biophysics, Institute of Health Sciences, Federal University of Bahia, Av. Reitor Miguel Calmon S/N, Salvador 40231-300, BA, Brazil.ORCID 0000-0002-8975-3871
Maria de Fátima Dias CostaLaboratory of Neurochemistry and Cellular Biology, Department of Biochemistry and Biophysics, Institute of Health Sciences, Federal University of Bahia, Av. Reitor Miguel Calmon S/N, Salvador 40231-300, BA, Brazil.ORCID 0000-0003-0916-2893
Funding
Fundação de Amparo à Pesquisa do Estado da Bahia BOL0284/2020National Council for Scientific and Technological Development EU-Process No. 407833/2023-4National Council for Scientific and Technological Development PI SLC Fellowship 312388/2021-7
6 · The paper itself
Abstract
The cells in the central nervous system (CNS) can adapt to injury and inflammation through structural and functional changes, many of which are mediated by the kynurenine pathway (KP). Studies using glia-neuron co-cultures showed that the biflavonoid agathisflavone (FAB), purified from the leaves of
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Agathisflavone Modulates the Kynurenine Pathway and Glial Inflammatory Responses with Implications for Neuroprotection. · full record | OpenQuestion