Evidence map›Paper›PMID 41465280›Full record

ArticleInternational journal of molecular sciences2025

Complex Relationships Between Homologous Recombination Deficiency (HRD) Score and Mutational Status of Homologous Recombination Repair (HRR) Genes in Prostate Carcinomas.

Aglaya G Iyevleva, Svetlana N Aleksakhina, Anna P Sokolenko, Ekaterina A Otradnova, Alisa S Nikitina, Kira A Kashko, Maria V Syomina, Anna D Shestakova, Ekaterina S Kuligina, Natalia S Morozova and 31 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Breast-Ovarian Hereditary Cancer Syndrome: BeyondCurrent oncology (Toronto, Ont.) · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

41 authors.

Aglaya G IyevlevaN.N. Petrov Institute of Oncology, Saint-Petersburg 197758, Russia.ORCID 0000-0001-5454-5186
Svetlana N AleksakhinaN.N. Petrov Institute of Oncology, Saint-Petersburg 197758, Russia.ORCID 0000-0002-2149-7728
Anna P SokolenkoN.N. Petrov Institute of Oncology, Saint-Petersburg 197758, Russia.ORCID 0000-0001-6304-1609
Ekaterina A OtradnovaN.N. Petrov Institute of Oncology, Saint-Petersburg 197758, Russia.
Alisa S NikitinaN.N. Petrov Institute of Oncology, Saint-Petersburg 197758, Russia.
Kira A KashkoN.N. Petrov Institute of Oncology, Saint-Petersburg 197758, Russia.ORCID 0009-0002-9410-9009
Maria V SyominaN.N. Petrov Institute of Oncology, Saint-Petersburg 197758, Russia.ORCID 0009-0003-3206-2871
Anna D ShestakovaN.N. Petrov Institute of Oncology, Saint-Petersburg 197758, Russia.
Ekaterina S KuliginaN.N. Petrov Institute of Oncology, Saint-Petersburg 197758, Russia.ORCID 0000-0002-2396-6540
Natalia S MorozovaN.N. Petrov Institute of Oncology, Saint-Petersburg 197758, Russia.ORCID 0009-0003-3335-872X
Sergey V PopovSaint Luke's Clinical Hospital, Saint Petersburg 194044, Russia.
Pavel V VyazovcevSaint Luke's Clinical Hospital, Saint Petersburg 194044, Russia.
Tatyana Y LuchkovaSaint Luke's Clinical Hospital, Saint Petersburg 194044, Russia.
Aleksey S PeremyshlenkoSaint Luke's Clinical Hospital, Saint Petersburg 194044, Russia.
Timur M TopuzovSaint Luke's Clinical Hospital, Saint Petersburg 194044, Russia.
Olga M GudkovaSaint Luke's Clinical Hospital, Saint Petersburg 194044, Russia.
Rashida V OrlovaSaint Petersburg City Oncological Clinic, Saint-Petersburg 197022, Russia.
Andrey V LevushkinSaint Petersburg City Oncological Clinic, Saint-Petersburg 197022, Russia.
Daniil O MoiseevSaint Petersburg City Oncological Clinic, Saint-Petersburg 197022, Russia.
Oksana N ShkodenkoStavropol Regional Oncological Clinic, Stavropol 355047, Russia.
Demyan V GubarevStavropol Regional Oncological Clinic, Stavropol 355047, Russia.
Aleksandr V DzyubaStavropol Regional Oncological Clinic, Stavropol 355047, Russia.
Irina Y PovorinaTula Regional Oncological Clinic, Tula 300039, Russia.
Anna V AgaevaArkhangelsk Regional Oncological Clinic, Arkhangelsk 163045, Russia.
Vladislav F KutyanKrasnodar Regional Oncological Clinic No. 1, Krasnodar 350040, Russia.
Mhitar M GrigoryanKrasnodar Regional Oncological Clinic No. 1, Krasnodar 350040, Russia.
Alexey N OrlovWMT Clinic, Krasnodar 350063, Russia.
Spartak I LefterovLeningrad Regional Clinical Hospital, Saint Petersburg 194291, Russia.
Aleksey V BelousovPenza Regional Oncological Clinic, Penza 440071, Russia.
Marina N NechaevaSeverodvinsk City Clinical Hospital No. 2, Severodvinsk 164500, Russia.ORCID 0009-0005-4128-2643
Elena N VorobyevaChelyabinsk Regional Clinical Center of Oncology and Nuclear Medicine, Chelyabinsk 454087, Russia.
Irina K AmirkhanovaVologda Regional Oncological Clinic, Vologda 160012, Russia.
Nadezhda V KryukovaVologda Regional Oncological Clinic, Vologda 160012, Russia.
Lyubov I ZatulivetrovaPyatigorsk Regional Oncological Clinic, Pyatigorsk 357502, Russia.
Aryuna B GomboevaBuryat Republican Oncological Clinic, Ulan-Ude 670047, Russia.
Vladimir N KrivtsovPskov Regional Oncological Clinic, Pskov 180004, Russia.
Olga I ShchiglikKarelian Republican Oncological Clinic, Petrozavodsk 185002, Russia.
Natalya V ProkudinaKaliningrad Regional Oncological Clinic, Kaliningrad 236016, Russia.
Natalya A ButuninaSaratov Regional Oncological Clinic, Saratov 410053, Russia.
Aleksey M BelyaevN.N. Petrov Institute of Oncology, Saint-Petersburg 197758, Russia.
Evgeny N ImyanitovN.N. Petrov Institute of Oncology, Saint-Petersburg 197758, Russia.ORCID 0000-0003-4529-7891

Funding

Russian Science Foundation 23-15-00262
6 · The paper itself

Abstract

Homologous recombination deficiency (HRD) resulting from inactivation of

Indexed as

MutationProstatic NeoplasmsRecombinational DNA RepairAgedBRCA1 ProteinBRCA2 ProteinFanconi Anemia Complementation Group N ProteinHomologous RecombinationHumansMaleMiddle AgedBRCA1 ProteinBRCA2 ProteinBRCA2 protein, humanFanconi Anemia Complementation Group N Proteinhomologous recombination deficiencyHRD scoremutations in homologous recombination repair genesprostate cancer

Identifiers

PMID41465280
PMCPMC12732970

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.