Evidence map›Paper›PMID 41465275›Full record

ReviewInternational journal of molecular sciences2025

Genetic Determinants of Progressive Pulmonary Fibrosis: A Comprehensive Review.

Ardak Zhumagaliyeva, Joanna Chorostowska-Wynimko, Aleksandra Jezela-Stanek

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ardak ZhumagaliyevaDepartment of Family Medicine No.2, Astana Medical University, Astana 010000, Kazakhstan.
Joanna Chorostowska-WynimkoDepartment of Genetics and Clinical Immunology, National Institute of Tuberculosis and Lung Diseases, 01-138 Warsaw, Poland.
Aleksandra Jezela-StanekDepartment of Genetics and Clinical Immunology, National Institute of Tuberculosis and Lung Diseases, 01-138 Warsaw, Poland.ORCID 0000-0001-9814-0324

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Progressive pulmonary fibrosis (PPF) encompasses fibrosing interstitial lung diseases marked by relentless scarring of the lungs, leading to respiratory failure. Although its pathogenesis remains incompletely understood, recent genetic discoveries have shed light on the molecular mechanisms that drive PPF onset and progression. This comprehensive review summarizes current knowledge of PPF genetics, highlighting both rare pathogenic variants and more common susceptibility polymorphisms. Key genetic contributors include telomere maintenance genes, surfactant protein genes, and the

Indexed as

Genetic Predisposition to DiseaseIdiopathic Pulmonary FibrosisPulmonary FibrosisDisease ProgressionDNA MethylationEpigenesis, GeneticHumansMucin-5BMUC5B protein, humanMucin-5Bepigeneticsgenetic variantsidiopathic pulmonary fibrosisMUC5B promoterprecision medicineprogressive pulmonary fibrosissurfactant protein genestelomere biology genes

Identifiers

PMID41465275
PMCPMC12732592

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.