Evidence map›Paper›PMID 41465197›Full record

ArticleInternational journal of molecular sciences2025

Capacitance-Driven Modulation of Cardiac Impulse Conduction by an Intramembrane Molecular Photoswitch.

Chiara Florindi, Alessio Ostini, Chiara Bertarelli, Jan P Kucera, Francesco Lodola

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Chiara FlorindiDepartment of Biotechnology and Biosciences, University of Milano-Bicocca, 20126 Milan, Italy.ORCID 0000-0002-5917-6356
Alessio OstiniDepartment of Physiology, University of Bern, 3012 Bern, Switzerland.
Chiara BertarelliCenter for Nano Science and Technology, Istituto Italiano di Tecnologia, 20134 Milan, Italy.
Jan P KuceraDepartment of Physiology, University of Bern, 3012 Bern, Switzerland.ORCID 0000-0003-0310-6962
Francesco LodolaDepartment of Biotechnology and Biosciences, University of Milano-Bicocca, 20126 Milan, Italy.ORCID 0000-0002-3506-5619

Funding

European Society of Cardiology Scientific Exchange Grant from the Working Group on Cardiac Cellular ElectrophysiologyItalian Ministry of Universities and Research ID 2022-NAZ-0595Swiss National Science Foundation 320030-227774
6 · The paper itself

Abstract

Membrane-targeted photoswitches are emerging as innovative tools to modulate cardiac excitability with high spatiotemporal precision. Ziapin2, a membrane-integrating azobenzene derivative, undergoes light-driven trans-cis isomerization that alters membrane capacitance (C

Indexed as

Action PotentialsAzo CompoundsCell MembraneElectric CapacitanceHeart Conduction SystemMyocytes, CardiacAnimalsCells, CulturedLightMembrane PotentialsMiceAzo Compoundsazobenzene photoswitchcapacitance modulationcardiac impulse propagation

Identifiers

PMID41465197
PMCPMC12732376

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.