ArticleGenes2025
Study on the Developmental Differences Between Female and Male Early Embryos in Cattle In Vivo.
Article in Genes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Sex-biased transcriptome in in vitro produced bovine early embryos.Cell & bioscience · 2025Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
backgroundThe developmental differences between female and male early embryos regarding sex development remain a topic of controversy.
objectivesThis study aims to investigate whether there are significant developmental differences between female and male bovine embryos during in vivo development.
methodsThe CIDR + FSH + PGF2α + GnRH method was employed to induce superovulation in 20 donor cows. Subsequently, artificial insemination was performed on the donor cows using high-purity X and Y frozen semen, with 10 cows receiving each type of semen. Seven days later, the embryos were flushed from the donor cows. The flushed embryos underwent embryonic sex determination, followed by immunofluorescence analysis to observe proliferation and apoptosis, and finally, RT-PCR was conducted to detect genes associated with proliferation and apoptosis.
resultsThe results indicated that the sex ratio of embryos obtained through artificial insemination using X/Y semen did not significantly differ based on semen purity (
conclusionsThe above results indicate that during in vivo development of bovine early embryos, male embryos develop at a faster rate than female embryos.
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