Evidence map›Paper›PMID 41465005›Full record

ReviewFoods (Basel, Switzerland)2025

Monitoring and Maintaining the Freshness of Royal Jelly: A Review of Analytical Approaches and Preservation Technologies.

Yu Zhang, Jing Sun, Rui Chen, Lin Zhang, Xuan Ma, Jiangying Heng, Feng Wang, Xiaofeng Xue

Abstract readReview
In one paragraph

Review in Foods (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yu ZhangCollege of Biochemical Engineering, Beijing Union University, Beijing 100101, China.
Jing SunState Key Laboratory of Resource Insects, Institute of Apiculture Research, Chinese Academy of Agricultural Sciences, Beijing 100193, China.
Rui ChenState Key Laboratory of Resource Insects, Institute of Apiculture Research, Chinese Academy of Agricultural Sciences, Beijing 100193, China.ORCID 0000-0002-7840-2785
Lin ZhangState Key Laboratory of Resource Insects, Institute of Apiculture Research, Chinese Academy of Agricultural Sciences, Beijing 100193, China.
Xuan MaCollege of Biochemical Engineering, Beijing Union University, Beijing 100101, China.
Jiangying HengCollege of Biochemical Engineering, Beijing Union University, Beijing 100101, China.
Feng WangCollege of Biochemical Engineering, Beijing Union University, Beijing 100101, China.
Xiaofeng XueState Key Laboratory of Resource Insects, Institute of Apiculture Research, Chinese Academy of Agricultural Sciences, Beijing 100193, China.

Funding

Central Public-interest Scientific Institution Basal Research Fund MFSJKF2024-10National Key Research and Development Program 2023YFF1103804Natural Science Foundation of Beijing Municipality 6222057
6 · The paper itself

Abstract

Royal jelly, a high-value natural product rich in bioactive compounds, is highly susceptible to quality deterioration during storage and processing. However, current quality standards rely predominantly on basic physicochemical parameters and measuring the content of 10-hydroxy-2-decenoic acid (10-HDA), which fail to capture the comprehensive and dynamic nature of its freshness. This significant knowledge gap hinders the accurate assessment, prediction, and control of royal jelly quality throughout its supply chain. To address this limitation, this review systematically elucidates the molecular mechanisms underlying the deterioration of royal jelly freshness, including key pathways such as protein denaturation, Maillard reactions, enzymatic inactivation, and lipid oxidation, and analyzes the combined effects of intrinsic and extrinsic factors on its quality stability. It highlights the potential applications of novel biochemical markers-including major royal jelly proteins (MRJPs), Maillard reaction products, enzymatic activity indicators, and energy metabolites-while comparing the advantages and limitations of traditional chromatographic techniques with modern rapid sensing and spectroscopic analysis methods. Regarding preservation, a critical yet inadequately summarized area, this review systematically evaluates the applicability and limitations of various approaches, including low-temperature storage, drying treatments, non-thermal sterilization, microencapsulation, and modified atmosphere packaging. Future directions for integrated quality control are outlined, providing a theoretical basis for holistic quality management of royal jelly.

Indexed as

freshness evaluationpreservation technologiesquality deteriorationroyal jelly

Identifiers

PMID41465005
PMCPMC12732485

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.