ArticleFoods (Basel, Switzerland)2025
Development and Validation of a Selective Method to Quantify Low-Molecular-Mass Flavan-3-ols in Grapes and Wines.
Article in Foods (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Synergistic Enhancement of Phenolic Profile, Color Stability, and Aroma Complexity in Marselan Wine Through Co-Fermentation with Fu Tea.Foods (Basel, Switzerland) · 2026Article
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6 authors.
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Abstract
Quantifying low-molecular-mass (LMM) flavanols in wines is relevant because these compounds, though typically minor, reflect flavanol structural composition (seed vs. skin contributions) and relate to cultivar and winemaking technique. Their determination is challenging because oligomeric and polymeric tannins interfere with standard spectrophotometric assays. This study introduces a coupled procedure that isolates and selectively quantifies LMM flavan-3-ols by combining the well-established methylcellulose precipitation assay (MCP) to remove oligomers and polymers with dimethylaminocinnamaldehyde (DMAC) determination of the MCP supernatant. The sequential workflow uses DMAC specificity and sensitivity and minimizes interference caused by higher-mass flavanols. Additionally, samples are quantified following dilution in the highly stable MCP supernatant medium. A Small Flavanol Index (SFI, %) is also introduced, expressing the LMM fraction relative to methylcellulose-precipitable tannins and providing a descriptor of flavanol composition. The method was validated in terms of linearity, limits of detection and quantification (LOQ in the supernatant, 1.58 mg L
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