Evidence map›Paper›PMID 41464586›Full record

ReviewJournal of clinical medicine2025

Exercise Participation and Rehabilitation in Cardiomyopathies: An Updated Review.

Domitilla Russo, Cristina Gambardella, Maurizio Volterrani, Rosa Lillo, Massimo Volpe, Camillo Autore

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Domitilla RussoDepartment of Cardiology, Santo Spirito Hospital, 00193 Rome, Italy.
Cristina GambardellaUnità di Riabilitazione Cardio-Respiratoria, IRCCS San Raffaele Cassino, 03043 Cassino, Italy.
Maurizio VolterraniIRCSS San Raffaele Roma, Università San Raffaele-Uniroma 5, 00166 Rome, Italy.
Rosa LilloDepartment of Cardiovascular Sciences-Heart, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.
Massimo VolpeIRCSS San Raffaele Roma, Via di Val Cannuta 250, 00166 Rome, Italy.ORCID 0000-0002-9642-8380
Camillo AutoreDepartment of Cardiology and Respiratory Sciences, IRCCS San Raffaele Cassino, Via G. di Biasio, 1, 03043 Cassino, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiomyopathies, including hypertrophic (HCM), dilated (DCM), and arrhythmogenic (ACM) forms, represent a challenge in cardiovascular medicine, in particular regarding exercise participation and cardiac rehabilitation. Traditionally, physical activity was restricted in these patients due to concerns over arrhythmic risk and sudden cardiac death. However, current evidence suggests that individualized exercise programs, under clinical supervision, can enhance functional capacity, improve quality of life, and sometimes prognosis in selected patients. Contemporary European and North American guidelines suggest that participation in competitive sports may be reasonable for athletes with genetic cardiomyopathies, provided that individual risk is regularly and systematically reassessed. The aim of this review is to synthetize current evidence on exercise training, sports participation and rehabilitation in the three major cardiomyopathies-hypertrophic, dilated, and arrhythmogenic-which have informed the latest international guideline recommendations. Particular attention is given to the essential role of shared decision-making, highlighting the importance of a personalized approach based on the specific type of cardiomyopathy, arrhythmic risk stratification, and individual patient factors. In addition, the review addresses two emerging clinical scenarios: sports participation in patients with implantable cardioverter-defibrillators and current recommendations for genotype-positive/phenotype-negative individuals at risk of cardiomyopathy.

Indexed as

arrhythmogenic cardiomyopathycardiac rehabilitationcardiomyopathydilated cardiomyopathyexercisehypertrophic cardiomyopathysudden cardiac death

Identifiers

PMID41464586
PMCPMC12733826

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.