Screening of Differentially Expressed Genes Related to Growth, Development and Meat Quality Traits of Huanghuai Sheep Based on RNA-Seq Technology.

Wanli Han, Mengke Song, Fuxian Gao, Haoyuan Han, Huibin Shi, Kai Quan, Jun Li

Abstract read

In one paragraph

Article in Animals : an open access journal from MDPI, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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Authors and funding

7 authors.

Wanli HanCollege of Animal Science and Technology, Henan University of Animal Husbandry and Economy, Zhengzhou 450046, China.ORCID 0009-0004-4773-2652

Mengke SongCollege of Animal Science and Technology, Henan University of Animal Husbandry and Economy, Zhengzhou 450046, China.

Fuxian GaoCollege of Animal Science and Technology, Henan University of Animal Husbandry and Economy, Zhengzhou 450046, China.

Haoyuan HanCollege of Animal Science and Technology, Henan University of Animal Husbandry and Economy, Zhengzhou 450046, China.

Huibin ShiCollege of Animal Science and Technology, Henan University of Animal Husbandry and Economy, Zhengzhou 450046, China.

Kai QuanCollege of Animal Science and Technology, Henan University of Animal Husbandry and Economy, Zhengzhou 450046, China.ORCID 0000-0002-0015-8663

Jun LiCollege of Animal Science and Technology, Henan University of Animal Husbandry and Economy, Zhengzhou 450046, China.

Funding

Henan Agricultural Research System HARS-22-15-SKey Technology Research Project of Henan Province 232102110007 252102110020 232102111047Natural Science Foundation of Henan 242300420148Program for Innovative Research Team in University of Henan Province 25IRTSTHN027

6 · The paper itself

Abstract

Huanghuai sheep, a newly developed meat-specialized breed in China, are valued for their rapid growth and high meat quality, but the optimal slaughter age and the molecular basis of these traits remain poorly understood. Gaining insight into these mechanisms is vital for improving production efficiency and guiding molecular breeding in this economically important breed. Although previous studies have described the phenotypic characteristics of Huanghuai sheep, the genetic regulatory networks controlling muscle growth and meat quality at different developmental stages remain unclear. No thorough analysis of growth traits and transcriptomic variations across key age points has been conducted. Therefore, in this study, we aimed to evaluate how growth stage influences muscle development, carcass characteristics, and meat quality in Huanghuai sheep by integrating phenotypic characterization with transcriptomic profiling to identify key genes and molecular pathways underlying these economically important traits throughout development. Sixty Huanghuai sheep were assigned to three groups (twenty per group) representing key developmental stages (3, 9, and 18 months of age). Carcass traits and meat quality were evaluated. RNA sequencing of the

Indexed as

correlation analysisgrowth and developmentHuanghuai sheepLongissimus dorsimeat quality traitstranscriptome

Identifiers

PMID41463897

DOI10.3390/ani15243612

PMCPMC12730065

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LicenceCC BY

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.