Evidence map›Paper›PMID 41463717›Full record

ArticleAntibiotics (Basel, Switzerland)2025

Design, Synthesis, and Antimalarial Evaluation of New Spiroacridine Derivatives.

Misael de Azevedo Teotônio Cavalcanti, Sonaly Lima Albino, Karla Joane da Silva Menezes, Wallyson Junio Santos de Araújo, Fernanda de França Genuíno Ramos Campos, Malu Maria Lucas Dos Reis, Inês Morais, Denise Maria Figueiredo Araújo Duarte, Igor José Dos Santos Nascimento, Valnês da Silva Rodrigues-Junior and 2 more

Abstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Misael de Azevedo Teotônio CavalcantiPrograma de Pós-Graduação em Ciências Farmacêuticas (PPGCF), Universidade Estadual da Paraíba (UEPB), Campina Grande 58429-500, PB, Brazil.
Sonaly Lima AlbinoPrograma de Pós-Graduação em Ciências Farmacêuticas (PPGCF), Universidade Estadual da Paraíba (UEPB), Campina Grande 58429-500, PB, Brazil.ORCID 0000-0002-2904-036X
Karla Joane da Silva MenezesLaboratório de Desenvolvimento e Síntese de Fármacos (LDSF), Universidade Estadual da Paraíba (UEPB), Campina Grande 58429-500, PB, Brazil.
Wallyson Junio Santos de AraújoLaboratório de Desenvolvimento e Síntese de Fármacos (LDSF), Universidade Estadual da Paraíba (UEPB), Campina Grande 58429-500, PB, Brazil.ORCID 0000-0002-7893-9136
Fernanda de França Genuíno Ramos CamposLaboratório de Desenvolvimento e Síntese de Fármacos (LDSF), Universidade Estadual da Paraíba (UEPB), Campina Grande 58429-500, PB, Brazil.
Malu Maria Lucas Dos ReisLaboratório de Desenvolvimento e Síntese de Fármacos (LDSF), Universidade Estadual da Paraíba (UEPB), Campina Grande 58429-500, PB, Brazil.ORCID 0000-0003-4480-680X
Inês MoraisGlobal Health and Tropical Medicine (GHTM), Associate Laboratory in Translation and Innovation Towards Global Health, LA-REAL, Instituto de Higiene e Medicina Tropical (IHMT), Universidade NOVA de Lisboa (UNL), Rua da Junqueira 100, 1349-008 Lisboa, Portugal.ORCID 0000-0003-3906-694X
Denise Maria Figueiredo Araújo DuarteGlobal Health and Tropical Medicine (GHTM), Associate Laboratory in Translation and Innovation Towards Global Health, LA-REAL, Instituto de Higiene e Medicina Tropical (IHMT), Universidade NOVA de Lisboa (UNL), Rua da Junqueira 100, 1349-008 Lisboa, Portugal.
Igor José Dos Santos NascimentoPrograma de Pós-Graduação em Ciências Farmacêuticas (PPGCF), Universidade Estadual da Paraíba (UEPB), Campina Grande 58429-500, PB, Brazil.ORCID 0000-0002-2664-4336
Valnês da Silva Rodrigues-JuniorPrograma de Pós-Graduação em Produtos Naturais e Sintéticos Bioativos (PgPNSB), Departamento de Ciências Farmacêuticas, Universidade Federal da Paraíba (UFPB), João Pessoa 58051-900, PB, Brazil.ORCID 0000-0002-4849-2249
Fátima NogueiraGlobal Health and Tropical Medicine (GHTM), Associate Laboratory in Translation and Innovation Towards Global Health, LA-REAL, Instituto de Higiene e Medicina Tropical (IHMT), Universidade NOVA de Lisboa (UNL), Rua da Junqueira 100, 1349-008 Lisboa, Portugal.ORCID 0000-0003-0313-0778
Ricardo Olímpio de MouraPrograma de Pós-Graduação em Ciências Farmacêuticas (PPGCF), Universidade Estadual da Paraíba (UEPB), Campina Grande 58429-500, PB, Brazil.ORCID 0000-0002-1590-3750

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

acridinedihydrofolate reductasemalariaMM-PBSAmolecular dockingmolecular dynamicssynthesisthymidylate synthasetropical parasitic diseases

Identifiers

PMID41463717
PMCPMC12730060

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.