Evidence map›Paper›PMID 41463715›Full record

ArticleAntibiotics (Basel, Switzerland)2025

Household Knowledge of Clinical Risks, Storage, and Disposal of Leftover Antibiotics: A Multinational Study in Seven Developing Countries.

Katia Iskandar, Reham Kotb, Michelle Cherfane, Joumana Yeretzian, Julia Bou Dib, Bahia Chahine, Souheil Hallit, Rohul Amin, Mohamed Bahlol, Feten Fekih-Romdhane and 12 more

Abstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Katia IskandarDepartment of Biomedical Sciences, School of Pharmacy, Lebanese International University, Beirut P.O. Box 146404, Lebanon.ORCID 0000-0001-5544-6681
Reham KotbDepartment of Environmental and Public Health, College of Health Sciences, Abu Dhabi University, Abu Dhabi 59911, United Arab Emirates.
Michelle CherfaneINSPECT-LB (Institut National de Santé Publique, d'Épidémiologie Clinique et de Toxicologie-Liban), Beirut P.O. Box 12109, Lebanon.
Joumana YeretzianCenter for Collaborative Research Initiatives in Public Health, Higher Institute of Public Health, Saint Joseph University of Beirut, Riad El Solh, Beirut P.O. Box 11-5076, Lebanon.ORCID 0000-0001-5805-4915
Julia Bou DibCenter for Collaborative Research Initiatives in Public Health, Higher Institute of Public Health, Saint Joseph University of Beirut, Riad El Solh, Beirut P.O. Box 11-5076, Lebanon.ORCID 0009-0001-4343-287X
Bahia ChahineDepartment of Biomedical Sciences, School of Pharmacy, Lebanese International University, Beirut P.O. Box 146404, Lebanon.
Souheil HallitSchool of Medicine and Medical Sciences, Holy Spirit University of Kaslik, Jounieh P.O. Box 446, Lebanon.ORCID 0000-0001-6918-5689
Rohul AminBengal Overseas Ltd., Mohakhali, Dhaka 1212, Bangladesh.ORCID 0000-0002-7415-2096
Mohamed BahlolSpecialty of Pharmaceutical Management and Economics, Department of Pharmacy Practice and Clinical Pharmacy, Faculty of Pharmacy, Egyptian Russian University, Badr City 11829, Cairo Governorate, Egypt.ORCID 0000-0002-2990-2708
Feten Fekih-RomdhaneThe Tunisian Center of Early Intervention in Psychosis, Department of Psychiatry "Ibn Omrane", Razi Hospital, Manouba 2010, Tunisia.ORCID 0000-0002-2569-8017
Faten HamedDepartment of Biomedical Sciences, School of Pharmacy, Lebanese International University, Beirut P.O. Box 146404, Lebanon.ORCID 0009-0008-4379-7175
Mai HelmyDepartment of Psychology, College of Education, Sultan Qaboos University, Muscat P.O. Box 32, Oman.ORCID 0000-0002-7649-1358
Mohammed IrfanDepartment of Restorative Dentistry, School of Dentistry, Federal University of Pelotas, Pelotas 96020-010, Brazil.ORCID 0000-0003-0683-106X
Jayaseelan MurugaiyanDepartment of Biological Sciences, School of Engineering and Sciences (SEAS), SRM University-AP, Amaravati 522240, Andhra Pradesh, India.ORCID 0000-0002-1924-2988
Abdallah Y NaserDepartment of Applied Pharmaceutical Sciences and Clinical Pharmacy, Faculty of Pharmacy, Isra University, Amman P.O. Box 11622, Jordan.ORCID 0000-0001-8440-7446
Esra' O TaybehDepartment of Applied Pharmaceutical Sciences and Clinical Pharmacy, Faculty of Pharmacy, Isra University, Amman P.O. Box 11622, Jordan.ORCID 0000-0001-7493-7865
Nebojša PavlovićDepartment of Pharmacy, Faculty of Medicine, University of Novi Sad, Hajduk Veljkova 3, 21000 Novi Sad, Serbia.ORCID 0000-0002-9444-5830
Deema RahmeDepartment of Pharmacy Practice, Faculty of Pharmacy, Beirut Arab University, Beirut P.O. Box 11-5020, Lebanon.ORCID 0000-0003-4245-9699
Marwan AklDepartment of Biomedical Sciences, School of Pharmacy, Lebanese International University, Beirut P.O. Box 146404, Lebanon.
Pascale SalamehINSPECT-LB (Institut National de Santé Publique, d'Épidémiologie Clinique et de Toxicologie-Liban), Beirut P.O. Box 12109, Lebanon.
Ana TomasDepartment of Pharmacology, Toxicology, and Clinical Pharmacology, Faculty of Medicine, University of Novi Sad, Hajduk Veljkova 3, 21000 Novi Sad, Serbia.ORCID 0000-0003-2361-872X
Maarten Van DongenAMR Insights, 1017 EG Amsterdam, The Netherlands.ORCID 0000-0002-3212-3924

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSelf-medication with leftover antibiotics (SMLA) drives antimicrobial resistance (AMR), particularly in developing countries. This study examined knowledge-practice gaps regarding antibiotic use and handling among individuals with prior SMLA across seven developing countries.

methodsA cross-sectional study (February 2023-February 2024) included 3191 adults from Bangladesh, Brazil, Egypt, India, Jordan, Lebanon, and Serbia who reported previous leftover antibiotic use. The questionnaires assessed knowledge of antibiotic use (15 items), resistance (12 items), and SMLA risks (15 items). Storage and disposal practices were evaluated using dichotomized correct/incorrect measures.

resultsParticipants demonstrated above-average knowledge scores as follows: antibiotic use (54.4 ± 8.4), resistance (43.3 ± 6.1), and SMLA risks (58.4 ± 10.3). However, substantial practice gaps emerged. Only 21.9% properly disposed of leftover antibiotics, while 47.0% used household garbage. For storage, 55.1% used appropriate methods, but 32.6% stored antibiotics inappropriately, and 12.8% lacked protocols. Serbian participants showed the highest SMLA risk knowledge (64.3 ± 10.6), Bangladeshi participants the lowest (52.0 ± 8.5,

conclusionsDespite extensive theoretical knowledge, unsafe medication practices persist, revealing a critical knowledge-practice gap. Our findings challenge education-focused AMR approaches, suggesting cognitive awareness alone cannot drive behavioral change. Effective interventions must address structural barriers, cultural factors, and individual health beliefs beyond traditional knowledge-deficit models.

Indexed as

developing countriesdisposalhouseholdleftover antibioticsself-medicationstorage

Identifiers

PMID41463715
PMCPMC12729722

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.