ArticleAntibiotics (Basel, Switzerland)2025
Knowledge and Support for Antimicrobial Stewardship Does Not Necessarily Translate into Good Practice: Survey in a Tertiary Hospital in Moldova, May-June 2024.
Article in Antibiotics (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
BACKGROUND/
objectivesAntimicrobial resistance (AMR) is an increasing problem globally, largely driven by the overuse and misuse of antibiotics. In Moldova, physicians are frequently not following recommendations regarding the use of antimicrobials. Despite the adoption of a national strategy to combat AMR, information on healthcare professionals' knowledge, attitudes, and practices (KAP) related to antimicrobial stewardship (AMS) remains limited. This study aimed to assess KAP related to AMS among staff at a tertiary hospital.
methodsWe surveyed employees of the Republican Clinical Hospital between 20 May and 30 June 2024. We interviewed doctors, nurses, pharmacists, clinical pharmacologists, and epidemiologists using a structured, self-administered questionnaire. The instrument assessed their KAP regarding antimicrobial stewardship. We analyzed the data collected using descriptive statistics and tests of association.
resultsAmong 138 participants, 65% were female and 54% were nurses. A high proportion demonstrated good knowledge (87%) and a positive attitude (78%) towards AMS. However, only 31% reported good stewardship-related practices. Significant associations were observed between knowledge and attitude (
conclusionsThese findings reveal a disconnect between knowledge, attitudes, and practical implementation of AMS principles. While healthcare professionals were knowledgeable and well-intentioned, practice remains inconsistent. This suggests that effective AMS interventions must combine individual training with structural support at the institutional level. Tailored strategies should address both general awareness and hospital-specific factors contributing to AMR.
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