Evidence map›Paper›PMID 41463680›Full record

ArticleAntibiotics (Basel, Switzerland)2025

Validation of Automated Bacterial Suspension Preparation by Colibri

Robin Vanstokstraeten, Eveline Van Honacker, Kristof Emmerechts, Zan Janssen, Charlotte Michel, Goran Van Der Kelen, Kristof Vandoorslaer, Deborah De Geyter, Bram Vanmechelen

Abstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Robin VanstokstraetenDepartment of Microbiology and Infection Control, Universitair Ziekenhuis Brussel (UZ Brussel), 1090 Brussels, Belgium.ORCID 0000-0002-5589-502X
Eveline Van HonackerDepartment of Microbiology and Infection Control, Universitair Ziekenhuis Brussel (UZ Brussel), 1090 Brussels, Belgium.
Kristof EmmerechtsDepartment of Microbiology and Infection Control, Universitair Ziekenhuis Brussel (UZ Brussel), 1090 Brussels, Belgium.
Zan JanssenDepartment of Microbiology and Infection Control, Universitair Ziekenhuis Brussel (UZ Brussel), 1090 Brussels, Belgium.
Charlotte MichelDepartment of Microbiology and Infection Control, Universitair Ziekenhuis Brussel (UZ Brussel), 1090 Brussels, Belgium.ORCID 0000-0003-0250-2664
Goran Van Der KelenDepartment of Microbiology and Infection Control, Universitair Ziekenhuis Brussel (UZ Brussel), 1090 Brussels, Belgium.
Kristof VandoorslaerDepartment of Microbiology and Infection Control, Universitair Ziekenhuis Brussel (UZ Brussel), 1090 Brussels, Belgium.
Deborah De GeyterDepartment of Microbiology and Infection Control, Universitair Ziekenhuis Brussel (UZ Brussel), 1090 Brussels, Belgium.
Bram VanmechelenDepartment of Microbiology and Infection Control, Universitair Ziekenhuis Brussel (UZ Brussel), 1090 Brussels, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesOne of the most crucial responsibilities of clinical microbiology laboratories involves conducting precise and fast antimicrobial susceptibility testing (AST) on bacterial isolates, necessary to guide antibiotic therapy. Standardized disk diffusion, a manual AST method, consumes a significant amount of time and is error-prone. Total laboratory automation in microbiology should enable a lower workload, high traceability, and standardization in AST. Therefore, we examined the concordance at the categorical level between the manual reference method and a new automated approach for bacterial suspension preparation and plate streaking in AST.

methodsIn this study, we validated the automated bacterial suspension preparation by Colibri

resultsThe overall categorical agreement between the two compared methods was 96.3% (2186/2269). We identified 2.7% (62/2269) minor errors, 1.6% (17/1047) major errors, and 0.4% (4/1121) very major errors. However, it is noteworthy that after retesting the discrepant results, the major errors were reduced to 0.4% and the very major errors were reduced to 0%.

conclusionsThe combination of Colibri

Indexed as

antibiotic susceptibility testingColibridisk diffusionRadiantotal lab automationWASPWASPLab

Identifiers

PMID41463680
PMCPMC12729282

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.