Evidence map›Paper›PMID 41463660›Full record

ReviewBioengineering (Basel, Switzerland)2025

Translating AI to the Bedside with Physician Buy-In: Recommendations from a Meta-Analysis and Systematic Review of the Literature.

Grace Hwang, Seyyed Sina Hejazian, Alireza Vafaei Sadr, Jennifer K Wagner, Pingxu Hao, Ajith Vemuri, Yuki Kawamura, Khalid Nawab, Shadi Hijjawi, Ramin Zand and 1 more

Abstract readReview
In one paragraph

Review in Bioengineering (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Grace HwangCollege of Medicine, Penn State University, Hershey, PA 17033, USA.ORCID 0009-0008-3610-5214
Seyyed Sina HejazianDepartment of Neurology, Penn State University College of Medicine, Hershey, PA 17033, USA.ORCID 0000-0002-8448-1539
Alireza Vafaei SadrDepartment of Public Health Sciences, Penn State University College of Medicine, Hershey, PA 17033, USA.ORCID 0000-0002-5733-6678
Jennifer K WagnerSchool of Engineering Design and Innovation, Penn State University, University Park, PA 16827, USA.ORCID 0000-0002-2278-0306
Pingxu HaoSchool of Engineering Design and Innovation, Penn State University, University Park, PA 16827, USA.
Ajith VemuriDepartment of Neurology, Penn State University College of Medicine, Hershey, PA 17033, USA.ORCID 0009-0005-5603-1732
Yuki KawamuraSchool of Clinical Medicine, University of Cambridge, Cambridge CB2 0AH, UK.ORCID 0000-0003-2137-6464
Khalid NawabDepartment of Medicine, Penn State University College of Medicine, Hershey, PA 17033, USA.ORCID 0000-0002-1824-413X
Shadi HijjawiDepartment of Medicine, Penn State University College of Medicine, Hershey, PA 17033, USA.ORCID 0000-0002-6471-5633
Ramin ZandDepartment of Neurology, Penn State University College of Medicine, Hershey, PA 17033, USA.ORCID 0000-0002-9477-0094
Vida AbediDepartment of Public Health Sciences, Penn State University College of Medicine, Hershey, PA 17033, USA.ORCID 0000-0001-7689-933X

Funding

Machine Learning Prediction of 1-Year Mortality and Recurrence after Ischemic Stroke Using Enriched EHR dataR01NS128986 · NINDS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI Vida Abedi, Ramin Zand · 2023 to 2026
$2.6M
NIH HHS 1UL1TR002014-25NINDS NIH HHS R01 NS128986
6 · The paper itself

Abstract

backgroundArtificial intelligence (AI) is increasingly being used in healthcare. Despite its promise, physicians and trainees remain cautiously optimistic. This systematic review and meta-analysis aimed to assess knowledge and attitudes toward AI and to provide recommendations for AI buy-in by physicians.

methodsSearches of PubMed-OVID-IEEE-Scopus, and Web-of-Science for studies in 2013-2024 identified 11,437 records. One-hundred-and-fifteen met inclusion criteria. Fifty-three studies reported quantitative data on physicians'/trainees' knowledge and were included in the meta-analysis.

resultsOur meta-analysis estimated that only 19.6% of physicians and trainees have high overall AI knowledge, while 36.3% have low knowledge. Fifty-five studies evaluated the depth of AI knowledge. These studies consistently concluded that most physicians or trainees possess only moderate conceptual knowledge of AI, and their technical knowledge is usually limited. Qualitative evaluations also highlighted that a high level of conceptual AI knowledge is associated with greater receptiveness to AI implementation in medicine. We identified five major barriers to translating AI to the bedside with physician buy-in.

conclusionAlthough physicians and trainees are generally receptive to AI, many barriers hinder adoption. To address them, we recommend establishing standardized AI education and workforce training, involving clinicians early in AI design, clarifying legal and regulatory issues, leveraging insights from clinical decision support system implementation to reduce workflow challenges, and integrating patient-centered communication principles to enhance trust and transparency.

Indexed as

artificial intelligenceattitudeknowledgephysician buy-in

Identifiers

PMID41463660
PMCPMC12729787

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.