ArticleBioengineering (Basel, Switzerland)2025
In Vitro Experimental and Numerical Simulation Study on the Influence of Uniaxial Cyclic Compression on Cytoskeletal Structure.
Article in Bioengineering (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
While research on cellular responses to cyclic compression has predominantly focused on proliferation and differentiation, changes in cell orientation and force distribution within the cytoskeleton represent crucial biomechanical aspects that remain less explored. This study aimed to design a programmable device for applying uniaxial cyclic compression to cells and analyze actin filament reorientation following specific compression regimens. A programmable device was developed to apply uniaxial cyclic compression. A finite element model of a viscoelastic cell incorporating actin filaments was developed to evaluate cell membrane strain. Statistical analysis included Pearson correlation to assess the relationship between actin filament orientation and membrane strain, following normality confirmation with the Kolmogorov-Smirnov test. Student's
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.