Lower Limb Biomechanical Outcomes Following Endoprosthetic Reconstruction for Distal Femur and Proximal Tibia Bone Tumors: A Systematic Review and Meta-Analysis.

Yidan Gao, Bojian Yang, Quan Zhang, Guangming Hu, Yancheng Liu, Kuan Zhang, Jun Sun, Songhua Yan

Abstract readReview

In one paragraph

Review in Bioengineering (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yidan GaoSchool of Biomedical Engineering, Capital Medical University, Beijing 100069, China.ORCID 0009-0005-1793-8411

Bojian YangSchool of Biomedical Engineering, Capital Medical University, Beijing 100069, China.

Quan ZhangSchool of Biomedical Engineering, Capital Medical University, Beijing 100069, China.ORCID 0009-0000-6862-9022

Guangming HuSchool of Biomedical Engineering, Capital Medical University, Beijing 100069, China.

Yancheng LiuDepartment of Bone and Soft Tissue Tumor Oncology, Tianjin Hospital, Tianjin 300211, China.

Kuan ZhangSchool of Biomedical Engineering, Capital Medical University, Beijing 100069, China.

Jun SunDepartment of Neurology, Xuanwu Hospital, Capital Medical University, Beijing 100053, China.

Songhua YanSchool of Biomedical Engineering, Capital Medical University, Beijing 100069, China.ORCID 0000-0002-8585-638X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Given the higher incidence of bone tumors in younger populations, achieving post-operative biomechanical stability is critical to maintaining long-term mobility. The objective of this study was to evaluate the biomechanical impact of endoprosthetic reconstruction in patients with distal femur and proximal tibia bone tumors in comparison with a control group. The Embase, Scopus, PubMed, and Cochrane databases were systematically searched until January 2025, according to PRISMA guidelines. Heterogeneity was assessed via Cochran's Q statistic and quantified using the I

Indexed as

biomechanicsbone neoplasmsendoprosthetic reconstructionknee arthroplasty

Identifiers

PMID41463607

DOI10.3390/bioengineering12121310

PMCPMC12730080

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.