Evidence map›Paper›PMID 41463590›Full record

ArticleBioengineering (Basel, Switzerland)2025

Reinvestigation of Absorption Spectroscopic Thermal Dynamics of Archaerhodopsin 3 Based Voltage Sensor QuasAr1.

Alfons Penzkofer, Arita Silapetere, Peter Hegemann

Abstract read
In one paragraph

Article in Bioengineering (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Alfons PenzkoferFakultät für Physik, Universität Regensburg, Universitätsstraße 31, D-93053 Regensburg, Germany.ORCID 0000-0002-7554-4593
Arita SilapetereExperimentelle Biophysik, Institut für Biologie, Humboldt Universität zu Berlin, Invalidenstraße 42, D-10115 Berlin, Germany.
Peter HegemannExperimentelle Biophysik, Institut für Biologie, Humboldt Universität zu Berlin, Invalidenstraße 42, D-10115 Berlin, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The long-time absorption spectroscopic development of the genetically encoded microbial rhodopsin fluorescent voltage indicator QuasAr1 at room temperature in the dark was reinvestigated, mainly theoretically. The data analysis indicates protein aggregation within one day to some ten-nanometer sized Mie scattering particles. The absorption coefficient spectra can be deduced from measured attenuation coefficient spectra by scattering contribution subtraction. The initially present protonated retinal Schiff base (PRSB) Ret_580 isomerized and then deprotonated to neutral retinal Schiff base (RSB). One part of Ret_580, Ret_580

Indexed as

absorption spectroscopic characterizationArchaerhodopsinfluorescent voltage sensorground-state deprotonationground-state isomerizationnumerical simulation of thermal dynamicsprotein aggregationQuasAr1Rayleigh and Mie scattering

Identifiers

PMID41463590
PMCPMC12729394

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.